Department of Oncology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, 214023, China.
Nursing Department, Wuxi Children's Hospital, Wuxi, 214023, China.
BMC Complement Med Ther. 2020 Jan 16;20(1):15. doi: 10.1186/s12906-019-2800-5.
Gastrointestinal cancer is one of the most common malignancies and imposes heavy burdens on both individual health and social economy. We sought to survey the effect of a self-care education program on quality of life and fatigue in gastrointestinal cancer patients who received chemotherapy.
Ninety-one eligible gastrointestinal cancer patients were enrolled in this study and 86 valid samples were analyzed. Data were acquired with a demographics questionnaire, endpoint multidimensional questionnaire and the European Organization for Research and Treatment of Cancer (EORTC) quality of life questionnaire QLQ-C30. The collected data were analyzed using SPSS software.
The self-care education intervention significantly improved the quality of life with respect to emotional function (p = 0.018), role function (p = 0.041), cognitive function (p = 0.038) and alleviated side effects such as nausea/vomiting (p = 0.028) and fatigue (p = 0.029). Further analysis demonstrated that the self-care education benefited total fatigue, affective fatigue and cognitive fatigue in gastrointestinal cancer patients regardless of baseline depression.
Our results suggested the beneficial effects of the self-care education in both quality of life and anti-fatigue in gastrointestinal cancer patients under chemotherapy. The self-care education could be considered as a complementary approach during combination chemotherapy in gastrointestinal cancer patients.
胃肠道癌症是最常见的恶性肿瘤之一，给个人健康和社会经济都带来了沉重的负担。我们旨在调查自我护理教育计划对接受化疗的胃肠道癌症患者的生活质量和疲劳感的影响。
本研究纳入了 91 名符合条件的胃肠道癌症患者，其中 86 份有效样本被分析。使用人口统计学问卷、终点多维问卷和欧洲癌症研究与治疗组织（EORTC）生活质量问卷 QLQ-C30 采集数据。使用 SPSS 软件分析收集的数据。
自我护理教育干预显著提高了生活质量，在情感功能（p=0.018）、角色功能（p=0.041）、认知功能（p=0.038）方面有改善，同时缓解了恶心/呕吐（p=0.028）和疲劳（p=0.029）等副作用。进一步分析表明，无论基线抑郁情况如何，自我护理教育都有益于胃肠道癌症患者的总疲劳、情感疲劳和认知疲劳。
我们的研究结果表明，自我护理教育对胃肠道癌症患者在化疗期间的生活质量和抗疲劳都有有益的影响。自我护理教育可以被视为胃肠道癌症患者联合化疗时的一种补充方法。
