疫苗压力与脑膜炎奈瑟菌研讨会，法国安纳西，2005年3月9日至11日

Workshop on vaccine pressure and Neisseria meningitidis, Annecy, France, 9-11 March 2005.

作者信息

Alonso Jean Michel, Gilmet Gregory, Rouzic Erwan Muros-Le, Nassif Xavier, Plotkin Stanley A, Ramsay Mary, Siegrist Claire-Anne, Stephens David S, Teyssou Remy, Vogel Ulrich

机构信息

Institut Pasteur, Paris, France.

出版信息

Vaccine. 2007 May 22;25(21):4125-9. doi: 10.1016/j.vaccine.2007.03.001. Epub 2007 Mar 19.

DOI:10.1016/j.vaccine.2007.03.001

PMID:17449149

Abstract

A 3-day workshop, "Vaccine pressure and Neisseria meningitidis", was held in Annecy, France, 9-11 March 2005, to summarize the current state of knowledge regarding N. meningitidis capsule switching and vaccine pressure from capsular polysaccharide-based N. meningitidis vaccines, including conjugates. Main discussion topics were the host-bacteria relationship and N. meningitidis population, worldwide experience of meningococcal vaccination, and using existing experience to shape the future of meningococcal vaccination strategies. The workshop concluded that there is no current evidence to suggest that serogroup C conjugate vaccine pressure has resulted in meningococcal serogroup switching or replacement.

摘要

2005年3月9日至11日，一场名为“疫苗压力与脑膜炎奈瑟菌”的为期三天的研讨会在法国安纳西举行，旨在总结关于脑膜炎奈瑟菌荚膜转换以及基于荚膜多糖的脑膜炎奈瑟菌疫苗（包括结合疫苗）所产生的疫苗压力的当前知识状况。主要讨论主题包括宿主与细菌的关系及脑膜炎奈瑟菌种群、全球脑膜炎球菌疫苗接种经验，以及利用现有经验塑造脑膜炎球菌疫苗接种策略的未来。研讨会得出结论，目前没有证据表明C群结合疫苗压力已导致脑膜炎奈瑟菌血清群转换或替代。