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四种水稻除草剂对硬骨鱼(钝齿兔脂鲤)某些代谢和毒理学参数的影响。

Effects of four rice herbicides on some metabolic and toxicology parameters of teleost fish (Leporinus obtusidens).

作者信息

Moraes Bibiana Silveira, Loro Vania Lúcia, Glusczak Lissandra, Pretto Alexandra, Menezes Charlene, Marchezan Enio, de Oliveira Machado Sérgio

机构信息

Departamento de Química - Laboratório de Bioquímica Adaptativa, Universidade Federal de Santa Maria (UFSM), 97105-900 Santa Maria, RS, Brazil.

出版信息

Chemosphere. 2007 Jul;68(8):1597-601. doi: 10.1016/j.chemosphere.2007.03.006. Epub 2007 Apr 23.

Abstract

Effects of different herbicides on acetylcholinesterase (AChE), catalase and TBARS formation in teleost fish (Leporinus obtusidens) were studied. Fish were exposed during 30 days at concentrations of herbicides used in rice field. AChE activity in the brain decreased significantly after exposure to the herbicides clomazone and quinclorac. However, AChE activity increased significantly in muscle tissue after exposure to clomazone, propanil and metsulfuron methyl. Fish exposed to quinclorac, propanil and metsulfuron methyl showed TBARS decreased levels in brain and muscle tissues. However, TBARS and catalase activity increased in liver tissue after clomazone and propanil exposure. This study pointed out long-term effects on AChE activity, oxidative stress and antioxidant enzyme catalase in tissues of L. obtusidens after exposure to environmentally relevant concentrations of rice field herbicides. These parameters have been used to monitor fish toxicity in rice field system.

摘要

研究了不同除草剂对硬骨鱼(钝齿脂鲤)乙酰胆碱酯酶(AChE)、过氧化氢酶和丙二醛(TBARS)形成的影响。将鱼暴露于稻田使用的除草剂浓度下30天。暴露于除草剂异恶草酮和二氯喹啉酸后,脑中的AChE活性显著降低。然而,暴露于异恶草酮、敌稗和甲基磺草酮后,肌肉组织中的AChE活性显著增加。暴露于二氯喹啉酸、敌稗和甲基磺草酮的鱼脑和肌肉组织中TBARS水平降低。然而,暴露于异恶草酮和敌稗后,肝脏组织中的TBARS和过氧化氢酶活性增加。本研究指出,暴露于环境相关浓度的稻田除草剂后,钝齿脂鲤组织中的AChE活性、氧化应激和抗氧化酶过氧化氢酶受到长期影响。这些参数已用于监测稻田系统中的鱼类毒性。

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