Barakat Lamia P, Schwartz Lisa A, Simon Katherine, Radcliffe Jerilynn
Department of Psychology, Drexel University, Philadelphia, PA 19104, USA.
J Behav Med. 2007 Jun;30(3):199-208. doi: 10.1007/s10865-007-9103-x. Epub 2007 Apr 24.
The objective of this study was to examine the role of coping strategies, specifically negative thinking, in mediating the association of pain with symptoms of anxiety and depression in adolescents with sickle cell disease. Fifty-two 12-18-year-old adolescents with sickle cell disease completed a daily pain diary and paper-and-pencil measures of pain, pain coping, depression and anxiety. Symptoms of depression and anxiety were within the non-clinical range. Preliminary analyses indicated that lower family income was associated with higher reports of pain and negative thinking. Mediation regression analyses supported negative thinking as mediating the association of: (1) pain intensity with depression, and (2) pain interference with daily activities with anxiety. Findings highlight negative thinking as a factor compromising adolescents' adaptation to sickle cell pain; however, further investigation is required to determine the mediating influence of pain coping. Associations for lower income emphasize the multiple risk factors experienced by many of these adolescents.
本研究的目的是探讨应对策略，特别是消极思维，在介导镰状细胞病青少年疼痛与焦虑和抑郁症状之间关联中的作用。52名12 - 18岁的镰状细胞病青少年完成了每日疼痛日记以及关于疼痛、疼痛应对、抑郁和焦虑的纸笔测量。抑郁和焦虑症状处于非临床范围内。初步分析表明，家庭收入较低与较高的疼痛报告和消极思维有关。中介回归分析支持消极思维介导了以下关联：(1)疼痛强度与抑郁之间的关联，以及(2)疼痛对日常活动的干扰与焦虑之间的关联。研究结果突出了消极思维是损害青少年适应镰状细胞疼痛的一个因素；然而，需要进一步研究以确定疼痛应对的中介影响。低收入的关联强调了这些青少年中许多人所经历的多种风险因素。
