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Galactose metabolism in relation to cataract formation in marsupials.

作者信息

Stephens T, Crollini C, Mutton P, Gupta J D, Harley J D

出版信息

Aust J Exp Biol Med Sci. 1975 Jun;53(3):233-9. doi: 10.1038/icb.1975.24.

DOI:10.1038/icb.1975.24
PMID:174538
Abstract

Erythrocytic galactokinase and/or galactose-1-phosphate uridyl transferase activity were low in many species of marsupials. However, cataract formation was observed only in pouch-young members of these species when reared on cow's milk. The galactose tolerance of young kangaroos was found to be greatly impaired, but improved rapidly and markedly at the stage of which the definitive structure of the ruminant type of stomach as in adults is formed. The combination of high absorption of galactose and low levels of galactokinase and/or transferase thus appears to determine the predisposition of pouch-young marsupials to galactose cataractogenesis.

摘要

相似文献

1
Galactose metabolism in relation to cataract formation in marsupials.
Aust J Exp Biol Med Sci. 1975 Jun;53(3):233-9. doi: 10.1038/icb.1975.24.
2
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引用本文的文献

1
A geographic approach to senile cataracts: possible links with milk consumption, lactase activity, and galactose metabolism.老年性白内障的地理分布研究:与牛奶消费、乳糖酶活性及半乳糖代谢的可能联系
Dig Dis Sci. 1982 Mar;27(3):257-64. doi: 10.1007/BF01296925.
2
Galactose-l-phosphate uridyl transferase activity in red cells of various animal species.不同动物物种红细胞中半乳糖-1-磷酸尿苷酰转移酶的活性。
Experientia. 1981 Jun;37(6):550-2. doi: 10.1007/BF01990042.