Altinok Ilhan, Capkin Erol
Faculty of Marine Science, Department of Fisheries Technology Engineering, Karadeniz Technical University, Surmene, Trabzon 61530, Turkey.
Toxicol Pathol. 2007 Apr;35(3):405-10. doi: 10.1080/01926230701230353.
Liver, spleen, trunk kidney, gills, and brain of rainbow trout (Oncorhynchus mykiss) were examined histologically after exposure to different concentrations of methiocarb (2.5 and 3.75 mg/L) or endosulfan (0.6 and 1.3 micro g/L) for 21 days. Histological recovery was also studied by maintaining the pesticide-exposed fish in a freshwater system for an additional 30 d. Lesions were not evident in liver, kidney, spleen, or brain of fish exposed to either concentration of methiocarb for 21 d. Lesions were observed in gills, liver, spleen, and trunk kidney (but not brain) of rainbow trout exposed to either concentration of endosulfan. There was no concentration-related effect observed on the histopathological lesions. After 30 days of recovery, fish had no histological lesions in gills, kidney, spleen, liver, or brain. Therefore all the changes observed during exposure were reversible.
将虹鳟（Oncorhynchus mykiss）暴露于不同浓度的灭多威（2.5和3.75毫克/升）或硫丹（0.6和1.3微克/升）21天后，对其肝脏、脾脏、体肾、鳃和脑进行了组织学检查。还通过将接触农药的鱼在淡水系统中再饲养30天来研究组织学恢复情况。暴露于任一浓度灭多威21天的鱼的肝脏、肾脏、脾脏或脑中均未出现明显病变。在暴露于任一浓度硫丹的虹鳟的鳃、肝脏、脾脏和体肾（但不是脑）中观察到病变。未观察到组织病理学病变与浓度相关的效应。恢复30天后，鱼的鳃、肾脏、脾脏、肝脏或脑中没有组织学病变。因此，暴露期间观察到的所有变化都是可逆的。
