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[中药调节免疫功能抗肝癌作用的研究进展]

[Progress in studies on anti-hepatoma effect of traditional Chinese medicine by adjusting immune function].

作者信息

Yang Jin-Xia, Wang Xue-Mei

机构信息

Department of Integrated Traditional Chinese Medicin, Western Medicine of Peking University First Hospital & Institute of Integrated TCM, Western Medicine of Peking University, Beijing 100034, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2007 Feb;32(4):281-4.

PMID:17455456
Abstract

We surveyed the literatures domestic and abroad, and summarized traditional Chinese medicine (single or complex prescription) with anti-hepatoma effects by adjusting immune function. Traditional Chinese medicine showed great advantages in improving the immune system function of the organism in various ways, so they could prohibit the generation and development of tumor, lessen the damage caused by chemotherapeutics, increase the sensitivity of chemotherapeutics, strengthen immune surveillance to tumor cells, elevate living quatity of patients and prolong their living time. It is very promising to exploit much more effective anti-tumor drugs from TCM.

摘要

我们查阅了国内外文献,总结了通过调节免疫功能发挥抗肝癌作用的中药(单味药或复方)。中药在多方面改善机体免疫系统功能方面显示出巨大优势,因此可抑制肿瘤的发生发展,减轻化疗药物所致损伤,增加化疗药物敏感性,增强对肿瘤细胞的免疫监视,提高患者生活质量并延长生存期。从中药中开发出更有效的抗肿瘤药物前景十分广阔。

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Functional roles of p38 mitogen-activated protein kinase in macrophage-mediated inflammatory responses.p38丝裂原活化蛋白激酶在巨噬细胞介导的炎症反应中的功能作用。
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3
Gecko crude peptides induce apoptosis in human liver carcinoma cells in vitro and exert antitumor activity in a mouse ascites H22 xenograft model.
壁虎粗肽在体外可诱导人肝癌细胞凋亡,并在小鼠腹水型H22异种移植模型中发挥抗肿瘤活性。
J Biomed Biotechnol. 2012;2012:743573. doi: 10.1155/2012/743573. Epub 2012 Oct 3.
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Traditional Chinese medicine and immune regulation.中医与免疫调节。
Clin Rev Allergy Immunol. 2013 Jun;44(3):229-41. doi: 10.1007/s12016-012-8332-0.
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Antitumor effect and mechanism of Gecko on human esophageal carcinoma cell lines in vitro and xenografted sarcoma 180 in Kunming mice.壁虎对人食管癌细胞系的体外抗肿瘤作用及机制以及对昆明小鼠移植性肉瘤180的作用
World J Gastroenterol. 2008 Jul 7;14(25):3990-6. doi: 10.3748/wjg.14.3990.