MEN 2A 综合征患者同时发生甲状腺髓样癌和甲状腺微小乳头状癌：1例报告
Simultaneous occurrence of medullary carcinoma and papillary microcarcinoma of thyroid in a patient with MEN 2A syndrome. report of a case.
作者信息
Giacomelli Laura, Guerriero Gabriella, Falvo Laura, Altomare Vittorio, Chiesa Carlo, Ferri Simone, Stio Francesco
机构信息
Department of Surgical Sciences, Policlinico Umberto I, University of Rome La Sapienza, Rome, Italy.
出版信息
Tumori. 2007 Jan-Feb;93(1):109-11. doi: 10.1177/030089160709300121.
We report a case of simultaneous multifocal medullary carcinoma and papillary microcarcinoma in a patient with several distinctive features of MEN 2A. The patient underwent total thyroidectomy and central lymph node dissection. The extreme rarity and pathological features of this occurrence are discussed. There is no known common cause of these 2 different tumor types; it may be a stochastic exception. However, several other possibilities such as a common precursor cell or a common tumorigenic stimulus offer interesting perspectives for speculation.
我们报告了一例同时患有多灶性髓样癌和乳头状微癌的患者，该患者具有MEN 2A的几个显著特征。患者接受了全甲状腺切除术和中央淋巴结清扫术。本文讨论了这种情况的极端罕见性和病理特征。这两种不同肿瘤类型尚无已知的共同病因；这可能是一个随机例外。然而，其他几种可能性，如共同的前体细胞或共同的致瘤刺激因素，为推测提供了有趣的视角。
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