Darwish A, Satir A A, Hameed T, Malik S, Aqel N
Department of Pathology and Surgery, Arabian Gulf University, Bahrain.
Malays J Pathol. 1995 Dec;17(2):103-7.
A 55-year-old female underwent total thyroidectomy for medullary carcinoma of the left lobe of the thyroid. The right lobe showed an incidental occult papillary carcinoma. There was also diffuse lymphocytic thyroiditis. Immunohistochemistry for calcitonin and thyroglobin confirmed the separate histogenesis for both carcinomas. The coexistence of medullarry and papillary carcinoma of the thyroid is rare and the literature usually documents mixed tumours with features of both carcinomas, rather than independent tumours, as in our case.
一名55岁女性因左叶甲状腺髓样癌接受了全甲状腺切除术。右叶发现了偶然的隐匿性乳头状癌。同时还存在弥漫性淋巴细胞性甲状腺炎。降钙素和甲状腺球蛋白的免疫组化证实了两种癌的不同组织发生。甲状腺髓样癌和乳头状癌共存的情况很少见,文献中通常记载的是具有两种癌特征的混合性肿瘤,而非像我们病例中的独立肿瘤。