Kobayashi K, Teramoto S, Maeta H, Ishiguro S, Mori T, Horie Y
Second Department of Surgery, Faculty of Medicine, Tottori University, Japan.
J Surg Oncol. 1995 Aug;59(4):276-9. doi: 10.1002/jso.2930590416.
We report a case of simultaneous occurrence of medullary carcinoma and papillary carcinoma of the thyroid in the same thyroid gland. Immunoreactivity of calcitonin, carcinoembryonic antigen, neuron specific enolase and thyroglobulin made a sharp distinction between both neoplasms of the thyroid. It appears reasonable to consider that simultaneous occurrence of medullary carcinoma and papillary carcinoma of the thyroid in this case does not have embryological or genetical significance.
我们报告了一例在同一个甲状腺内同时发生甲状腺髓样癌和乳头状癌的病例。降钙素、癌胚抗原、神经元特异性烯醇化酶和甲状腺球蛋白的免疫反应性使甲状腺的这两种肿瘤有了明显区别。在该病例中，甲状腺髓样癌和乳头状癌的同时发生似乎并无胚胎学或遗传学意义，这一观点似乎是合理的。
