Shankar Sandeep, Biswas Jyotirmay, Gopal Lingam, Bagyalakshmi R, Therese Lily, Borse Nishikant J
Medical and Vision Research Foundations, Sankara Nethralaya, College Road, Chennai, India.
Indian J Ophthalmol. 2007 May-Jun;55(3):226-7. doi: 10.4103/0301-4738.31949.
Endogenous intraocular infection of fungal etiology is extremely rare in an immunocompetent individual. Usually, an antecedent history of trauma, surgery, intravenous drug abuse or an immunocompromized state can be elicited. Scedosporium apiospermum is a known cause of keratomycosis after traumatic implantation and can cause fatal disseminated infection in immunocompromized patients. However, cases of S. apiospermum intraocular infection in immunocompetent individuals have been very rarely reported in literature. We report here a case of an anterior chamber exudative mass due to S. apiospermum in an immunocompetent individual which was managed successfully with anterior chamber wash and intravitreal injection of voriconazole.
在免疫功能正常的个体中，真菌性内源性眼内感染极为罕见。通常，可以引出外伤、手术、静脉药物滥用或免疫功能低下状态的既往史。尖端赛多孢是外伤植入后角膜真菌病的已知病因，可在免疫功能低下的患者中引起致命的播散性感染。然而，免疫功能正常个体发生尖端赛多孢眼内感染的病例在文献中报道极少。我们在此报告一例免疫功能正常个体因尖端赛多孢引起的前房渗出性肿物，通过前房冲洗和玻璃体内注射伏立康唑成功治疗。
