伏立康唑成功治疗创伤性棘孢曲霉性眼内炎

Scedosporium apiospermum traumatic endophthalmitis successfully treated with voriconazole.

作者信息

Zarkovic Andrea, Guest Stephen

机构信息

Department of Ophthalmology, Waikato Hospital, Hamilton, New Zealand.

出版信息

Int Ophthalmol. 2007 Dec;27(6):391-4. doi: 10.1007/s10792-007-9095-0. Epub 2007 Sep 28.

DOI:10.1007/s10792-007-9095-0

PMID:17901927

Abstract

We describe a case of traumatic endophthalmitis due to Scedosporium apiospermum that was successfully treated with a combination of intravitreal and systemic voriconazole. A high dose of 200 microg was used intravitreally without any apparent complications. A brief overview of voriconazole use for treatment of ocular infections is presented, and a comparison is made with antifungal agents traditionally used in ophathalmology.

摘要

我们描述了一例由伪阿利什霉引起的创伤性眼内炎，该病例通过玻璃体内注射与全身应用伏立康唑联合治疗成功治愈。玻璃体内使用了200微克的高剂量，未出现任何明显并发症。本文简要概述了伏立康唑在眼部感染治疗中的应用，并与眼科传统使用的抗真菌药物进行了比较。