早期采用玻璃体内注射伏立康唑治疗尖端赛多孢菌性眼内炎可使视力恢复。
Scedosporium apiospermum endopthalmitis treated early with intravitreous voriconazole results in recovery of vision.
作者信息
Belenitsky Monika Paroder, Liu Catherine, Tsui Irena
机构信息
Department of Ophthalmology, Montefiore Medical Center, Bronx, NY, USA.
出版信息
J Ophthalmic Inflamm Infect. 2012 Sep;2(3):157-60. doi: 10.1007/s12348-012-0063-0. Epub 2012 Feb 28.
AIM
The purpose of this study is to report a case of endogenous endopthalmitis caused by Scedosporium apiospermum with a favorable outcome and review previously reported cases, their treatment regimens and outcomes.
METHODS
An 83-year-old man with diabetes mellitus, no other immunocompromising risk factors, and a history of S. apiospermum endopthalmitis in the left eye developed endopthalmitis in the right eye. Within 72 h of presentation, he was treated with a pars plana vitrectomy and intravitreal voriconozole.
RESULTS
Vitreous cultures confirmed S. apiospermum. The patient responded to treatment, with a favorable outcome and full recovery of vision.
CONCLUSIONS
Recognition of S. apiospermum endopthalmitis and appropriate early intervention with pars plana vitrectomy and intravitreal voriconozole can lead to a favorable outcome with restoration of visual acuity.
目的
本研究旨在报告1例由尖端赛多孢菌引起的内源性眼内炎且预后良好的病例，并回顾既往报道的病例、其治疗方案及预后。
方法
一名83岁男性，患有糖尿病，无其他免疫功能低下的危险因素，左眼有尖端赛多孢菌性眼内炎病史，右眼发生了眼内炎。在就诊后72小时内，他接受了玻璃体切除术和平部玻璃体腔注射伏立康唑治疗。
结果
玻璃体培养证实为尖端赛多孢菌。患者对治疗有反应，预后良好，视力完全恢复。
结论
认识到尖端赛多孢菌性眼内炎并早期采用玻璃体切除术和平部玻璃体腔注射伏立康唑进行适当干预，可获得良好预后并恢复视力。
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