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阿根廷流行的人轮状病毒G9P[8]毒株的检测:VP7和NSP4基因的系统发育分析

Detection of human rotavirus G9P[8] strains circulating in Argentina: phylogenetic analysis of VP7 and NSP4 genes.

作者信息

Stupka Juan A, Parra Gabriel I, Gómez Jorge, Arbiza Juan

机构信息

Laboratorio de Gastroenteritis Virales, Departamento de Virología, INEI-ANLIS Dr. Carlos G. Malbrán, Buenos Aires, Argentina.

出版信息

J Med Virol. 2007 Jun;79(6):838-42. doi: 10.1002/jmv.20841.

Abstract

During the surveillance of rotavirus strains that were circulating in Argentinean children from 2000 to 2004, seven rotaviruses were detected bearing the genotype combination G9P[8]. The molecular characterization of the VP7 and NSP4 genes and the RNA migration patterns support the hypothesis that rotaviruses G9 could have been reintroduced into Argentina as a novel G9P[8] strain, rather than represent VP7 gene reassortants from G9P[6] strains that had been circulating previously in this country.

摘要

在对2000年至2004年期间阿根廷儿童中流行的轮状病毒株进行监测时,检测到7株具有G9P[8]基因型组合的轮状病毒。VP7和NSP4基因的分子特征以及RNA迁移模式支持以下假设:G9轮状病毒可能作为一种新型G9P[8]毒株重新引入阿根廷,而不是代表此前在该国流行的G9P[6]毒株的VP7基因重配株。

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