Jeays Adam David, Lawford Patricia Veronica, Gillott Richard, Spencer Paul A, Bardhan Karna Dev, Hose David Rodney
Medical Physics, University of Sheffield, United Kingdom.
World J Gastroenterol. 2007 Mar 7;13(9):1393-8. doi: 10.3748/wjg.v13.i9.1393.
After a meal the activity of the gut increases markedly as digestion takes place. Associated with this increase in activity is an increase in blood flow, which has been shown to be dependent on factors such as caloric content and constitution of the meal. Much qualitative work has been carried out regarding mechanisms for the presence of food in a section of gut producing increased blood flow to that section, but there are still many aspects of this process that are not fully understood. In this paper we briefly review current knowledge on several relevant areas relating to gut blood flow, focusing on quantitative data where available and highlighting areas where further research is needed. We then present new data on the effect of feeding on flow in the superior mesenteric artery. Finally, we describe a framework for combining this data to produce a single model describing the mechanisms involved in postprandial hyperaemia. For a section of the model, where appropriate data are available, preliminary results are presented.
进食后，随着消化过程的进行，肠道的活动显著增加。与这种活动增加相关的是血流量的增加，已证明血流量的增加取决于食物的热量含量和组成等因素。关于肠道某一部位存在食物导致该部位血流量增加的机制，已经进行了大量定性研究，但这一过程仍有许多方面尚未完全了解。在本文中，我们简要回顾了当前关于肠道血流量几个相关领域的知识，重点关注现有定量数据，并突出需要进一步研究的领域。然后，我们展示了进食对肠系膜上动脉血流影响的新数据。最后，我们描述了一个整合这些数据以生成一个描述餐后充血所涉及机制的单一模型的框架。对于该模型的一部分，在有适当数据的情况下，给出了初步结果。
