Lalloo U G, Becklake M R, Goldsmith C M
National Centre for Occupational Health, Department of Epidemiology, Johannesburg, South Africa.
Respiration. 1991;58(3-4):122-5. doi: 10.1159/000195911.
This study examined the effect of the standing versus the sitting position on spirometric indices in 94 healthy non-obese adult subjects (41 men and 53 women) with the order of testing randomised. On average all the spirometric indices examined, except the peak expiratory flow rate, were higher in the standing compared to the sitting position although the change was only significant at the 5% level for FEV1 in women. The fall in FEV1 with the change in position was statistically related to the ponderal index but not to age, height or the initial lung function level. A uniform posture for spirometry is recommended in epidemiological studies examining longitudinal trends in lung function, as well as in cross-sectional aetiological studies examining, for instance, the effects of environmental and/or occupational exposures. A uniform posture is also recommended for clinical studies which involve repeated measurements over time, for instance to measure the effect of treatment or the natural history of airways disease.
本研究对94名健康非肥胖成年受试者（41名男性和53名女性）进行了测试顺序随机化，以研究站立位与坐位对肺量计指标的影响。平均而言，除呼气峰值流速外，所有检测的肺量计指标在站立位时均高于坐位，尽管这种变化仅在女性的第1秒用力呼气容积（FEV1）达到5%的显著水平。FEV1随体位变化的下降与体质指数在统计学上相关，但与年龄、身高或初始肺功能水平无关。在研究肺功能纵向趋势的流行病学研究中，以及在例如研究环境和/或职业暴露影响的横断面病因学研究中，建议采用统一的姿势进行肺量计检查。对于涉及随时间重复测量的临床研究，例如测量治疗效果或气道疾病的自然史，也建议采用统一的姿势。
