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血液透析方案依从性不佳的患病率及后果

Prevalence and consequences of nonadherence to hemodialysis regimens.

作者信息

Denhaerynck Kris, Manhaeve Dominique, Dobbels Fabienne, Garzoni Daniela, Nolte Christa, De Geest Sabina

机构信息

Institute of Nursing Science, University of Basel, Basel, Switzerland.

出版信息

Am J Crit Care. 2007 May;16(3):222-35; quiz 236.

PMID:17460313
Abstract

Adherence to fluid restrictions and dietary and medication guidelines as well as attendance at prescribed hemodialysis sessions of a hemodialysis regimen are essential for adequate management of end-stage renal disease. A literature review was conducted to determine the prevalence and consequences of nonadherence to the different aspects of a hemodialysis regimen and the methodological obstacles in research on nonadherence. Nonadherence to the prescribed regimen is a common problem in hemodialysis and is associated with increased morbidity and mortality. Research on nonadherence is associated with 2 major obstacles: inconsistencies in definitions and invalid measurement methods. Further research is needed to validate measurement methods and to establish clinically relevant operational definitions of nonadherence.

摘要

坚持液体限制、饮食和药物指南以及按时参加规定的血液透析疗程对于终末期肾病的充分管理至关重要。进行了一项文献综述,以确定血液透析方案不同方面的不依从性的患病率和后果,以及不依从性研究中的方法学障碍。不遵守规定的方案是血液透析中的一个常见问题,与发病率和死亡率增加有关。不依从性研究存在两个主要障碍:定义不一致和测量方法无效。需要进一步研究以验证测量方法并建立临床上相关的不依从性操作定义。

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