Arena N, Venti G, Becchetti E, Baroni T, Donti E, Paludetti G, Bodo M
Istituto di Istologia ed Embriologia generale, Università di Sassari, Italia.
Acta Anat (Basel). 1991;141(4):311-5. doi: 10.1159/000147141.
The localization and distribution of some cytoskeletal protein components were studied by immunostaining methods in normal and ostosclerotic osteoblast-like cells. The protein components investigated were microtubules (beta-tubulin), intermediate filaments (vimentin), microfilaments (actin and myosin) and structural proteins (alpha-actinin and fibronectin). Although the mechanism is not yet clear, the alterations observed in the pathological cells could well play a role in the expression of otosclerosis.
通过免疫染色方法研究了正常和成骨硬化的成骨细胞样细胞中一些细胞骨架蛋白成分的定位和分布。所研究的蛋白成分包括微管（β-微管蛋白）、中间丝（波形蛋白）、微丝（肌动蛋白和肌球蛋白）以及结构蛋白（α-辅肌动蛋白和纤连蛋白）。尽管其机制尚不清楚，但在病理细胞中观察到的改变很可能在耳硬化症的表达中起作用。
