Tanswell I, Barrett D, Emm C, Lycett W, Charles C, Evans K, Hearing S D
Department of Gastroenterology, Staffordshire General Hospital, Stafford, United Kingdom.
JPEN J Parenter Enteral Nutr. 2007 May-Jun;31(3):205-11. doi: 10.1177/0148607107031003205.
The purpose of this study was to determine whether preassessment by a multidisciplinary nutrition team before percutaneous endoscopic gastrostomy (PEG) placement can reduce postprocedure mortality. This was a prospective single-center audit.
Patients who had been referred to the Gastroenterology Department for consideration of PEG placement between 1995 and 2004 were included. In the index year, 2003-2004, where a formal nutrition team assessment was commenced, 79 patients were enrolled into our study group on a consecutive basis. These patients were subdivided into 3 groups; group A, PEG placed (51 patients); group B, PEG not placed due to severe comorbidity (19 patients); and group C, PEG not placed as deemed unnecessary (9 patients). Comparison was made with previous years where no formal preassessment had occurred. At Staffordshire General Hospital, a comparison of mortality post-PEG placement was made between the index group and previous years. Secondary measures included complication rates and frequency of biochemical monitoring.
One week post-PEG mortality fell from 10%-20% in previous years to 0% in the index year (p < .02). This improved survival extended to 3 months postprocedure (p < .016). Three patients (6%) had biochemical evidence of refeeding syndrome postplacement. Biochemical monitoring was inadequate, with only 27/51 (53%) patients being completely monitored. No complications pertaining to the endoscopy were reported.
This study demonstrates that early post-PEG mortality can be reduced by preassessment of patients by a multidisciplinary nutrition team and is evidence supporting the recommendations of the National Confidential Enquiry into Patient Outcome and Death report.
本研究旨在确定经皮内镜下胃造口术(PEG)置管前由多学科营养团队进行预评估是否可降低术后死亡率。这是一项前瞻性单中心审计。
纳入1995年至2004年间被转介至胃肠病科考虑进行PEG置管的患者。在2003 - 2004年这一开展正式营养团队评估的索引年份,79例患者连续纳入我们的研究组。这些患者被分为3组;A组,进行了PEG置管(51例患者);B组,因严重合并症未进行PEG置管(19例患者);C组,因认为不必要未进行PEG置管(9例患者)。与之前未进行正式预评估的年份进行比较。在斯塔福德郡总医院,对索引组与之前年份PEG置管后的死亡率进行了比较。次要指标包括并发症发生率和生化监测频率。
PEG置管后1周死亡率从之前年份的10% - 20%降至索引年份的0%(p <.02)。这种生存率的提高持续到术后3个月(p <.016)。3例患者(6%)置管后有再喂养综合征的生化证据。生化监测不足,仅27/51(53%)的患者得到了全面监测。未报告与内镜检查相关的并发症。
本研究表明,多学科营养团队对患者进行预评估可降低PEG置管后的早期死亡率,这为支持《全国患者结果和死亡保密调查报告》的建议提供了证据。