外阴良性脂肪母细胞瘤样肿瘤：1例年轻患者病例报告

Benign lipoblastomalike tumor of the vulva: report of a case affecting a young patient.

作者信息

Atallah David, Rouzier Roman, Chamoun Marie Laurence, Mansour Fersan, Nabaa Toufic, Chababi Mirna, Duvillard Pierre, Chahine Georges

机构信息

Department of Gynecology, Hôtel Dieu de France University Hospital, Beirut, Lebanon.

出版信息

J Reprod Med. 2007 Mar;52(3):223-4.

PMID:17465291

Abstract

BACKGROUND

Mesenchymal vulvar tumors are rare, and a benign lipoblastomalike tumor may be confused with malignancy.

CASE

A 15-year-old patient consulted for a right labium tumefaction measuring 15 cm. After excision, histologic examination revealed a well-circumscribed and lobulated tumor. The lobules were composed of slender spindle cells showing slightly eosinophilic cytoplasm with indistinct boundaries, uniform nuclei with finely granular chromatin and no nucleoli. Scattered Signet-ring-type lipoblasts were observed. The background was myxoid, with a "chickenwire" capillary vascular network mimicking a myxoid liposarcoma. No mitotic figures, necrosis or pleomorphism was noted.

CONCLUSION

This mesenchymal tumor had adipocytic differentiation and no patent sign of malignancy, akin to infantile lipoblastoma. Because of the benign behavior of this tumor, complete excision without radiation is recommended.

摘要

背景

间质性外阴肿瘤罕见，一种良性脂肪母细胞瘤样肿瘤可能会与恶性肿瘤混淆。

病例

一名15岁患者因右侧阴唇肿物前来就诊，肿物大小为15厘米。切除后，组织学检查显示肿瘤边界清晰，呈分叶状。小叶由细长的梭形细胞组成，细胞质轻度嗜酸性，边界不清，细胞核均匀，染色质呈细颗粒状，无核仁。可见散在的印戒样脂肪母细胞。背景为黏液样，有“鸡笼”样毛细血管网络，类似黏液样脂肪肉瘤。未见有丝分裂象、坏死或异形性。