Wenger N S, Linn L S, Epstein M, Shapiro M F
Department of Medicine, University of California, Los Angeles.
Am J Public Health. 1991 Dec;81(12):1580-5. doi: 10.2105/ajph.81.12.1580.
We evaluated the effect of HIV antibody testing on sexual behavior and communication with sexual partners about AIDS risk among heterosexual adults at a clinic for sexually transmitted diseases.
We randomized 186 subjects to receive either AIDS education alone (the control group) or AIDS education, an HIV antibody test, and the test results (the intervention group). These subjects were then followed up 8 weeks later.
At follow-up, mean number of sexual partners decreased, but not differently between groups. However, compared with controls, HIV antibody test intervention subjects, all of whom tested negative, questioned their most recent sexual partner more about HIV antibody status (P less than 0.01), worried more about getting AIDS (P less than 0.03), and tended to use a condom more often with their last sexual partner (P = 0.05): 40% of intervention subjects vs 20% of controls used condoms, avoided genital intercourse, or knew their last partner had a negative HIV antibody test (P less than 0.005).
HIV antibody testing combined with AIDS education increases concern about HIV and, at least in the short term, may promote safer sexual behaviors. Additional strategies will be necessary if behaviors risky for HIV transmission are to be further reduced.
我们在一家性传播疾病诊所评估了艾滋病毒抗体检测对异性恋成年人的性行为以及与性伴侣就艾滋病风险进行沟通的影响。
我们将186名受试者随机分为两组,一组仅接受艾滋病教育(对照组),另一组接受艾滋病教育、艾滋病毒抗体检测及检测结果(干预组)。然后在8周后对这些受试者进行随访。
随访时,性伴侣的平均数量有所减少,但两组之间无差异。然而,与对照组相比,艾滋病毒抗体检测干预组的所有受试者检测结果均为阴性,他们更多地询问了其最近性伴侣的艾滋病毒抗体状况(P<0.01),更担心感染艾滋病(P<0.03),并且更倾向于在与最后一位性伴侣发生性行为时使用避孕套(P = 0.05):干预组40%的受试者与对照组20%的受试者使用了避孕套、避免了生殖器性交或知道其最后一位伴侣的艾滋病毒抗体检测结果为阴性(P<0.005)。
艾滋病毒抗体检测与艾滋病教育相结合会增加对艾滋病毒的关注,并且至少在短期内可能会促进更安全性行为。如果要进一步减少有感染艾滋病毒风险的行为,还需要其他策略。