Tarrier Nicholas, Gooding Patricia, Gregg Lynsey, Johnson Judith, Drake Richard
School of Psychological Sciences, University of Manchester, Zochonis Building, Brunswick Street, Manchester M13 9PL, UK.
Behav Res Ther. 2007 Sep;45(9):2090-7. doi: 10.1016/j.brat.2007.03.007. Epub 2007 Mar 18.
Suicide risk is thought to increase with a greater potential for activation of suicide-related schemas. Suicide schemas are less likely to be activated with reductions of emotional range associated with certain negative symptoms of schizophrenia. The study tested whether suicide risk would increase in patients with recent onset schizophrenia with increased potential for suicide schema activation as indicated by lower levels of specific negative symptoms that reflected emotional reactivity, namely emotional withdrawal and blunted affect. A logistic regression analysis of baseline data of 278 recent onset schizophrenic patients with a measure of suicide behaviour as the dependent variable and negative symptoms, delusions, hallucinations, depression, gender, episode, ethnicity, education, age, duration of untreated psychosis and substance use as independent variables was carried out. Emotional withdrawal, but not blunted affect was significant and negatively associated, and depression positively associated with suicide behaviour. There was evidence to indicate that restricted emotions are associated with reduced suicide risk as predicted.
自杀风险被认为会随着自杀相关图式激活的可能性增加而上升。随着与精神分裂症某些阴性症状相关的情绪范围缩小，自杀图式被激活的可能性降低。该研究测试了近期发病的精神分裂症患者中，自杀风险是否会因反映情绪反应性的特定阴性症状水平较低所表明的自杀图式激活可能性增加而上升，这些阴性症状即情感退缩和情感迟钝。以自杀行为测量值为因变量，阴性症状、妄想、幻觉、抑郁、性别、发作、种族、教育程度、年龄、未治疗精神病持续时间和物质使用为自变量，对278例近期发病的精神分裂症患者的基线数据进行了逻辑回归分析。情感退缩而非情感迟钝具有显著负相关性，抑郁与自杀行为呈正相关。有证据表明，如预期的那样，受限情绪与自杀风险降低有关。
