Andersson Karl-Erik, Christ George J
Wake Forest Institute for Regenerative Medicine, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA.
Mol Interv. 2007 Apr;7(2):79-86. doi: 10.1124/mi.7.2.8.
Regenerative medicine technologies cross the boundaries of numerous scientific fields, including cell and molecular biology, chemical and material sciences (i.e., nanotechnology), engineering, molecular genetics, physiology and pharmacology. As such, regenerative medicine truly represents an integrative and logical (r)evolution of medical science. This groundbreaking field of research has the potential to radically alter the treatment of diseases or disorders characterized by the lack of viable cells or tissues. The goal of this report is to review the current challenges and opportunities in the emerging field of regenerative medicine and to describe the role of the pharmacological sciences in the acceleration, optimization, and evaluation of engineered tissue function in the service of regenerative medicine technologies.
再生医学技术跨越了众多科学领域的界限,包括细胞与分子生物学、化学与材料科学(即纳米技术)、工程学、分子遗传学、生理学和药理学。因此,再生医学真正代表了医学科学的一次整合性且合乎逻辑的(r)进化。这个开创性的研究领域有可能从根本上改变对因缺乏活细胞或组织而导致的疾病或功能紊乱的治疗方式。本报告的目的是回顾再生医学这一新兴领域当前面临的挑战和机遇,并描述药理科学在加速、优化和评估工程组织功能以服务于再生医学技术方面所起的作用。