Biederman Joseph, Petty Carter R, Fried Ronna, Fontanella Jessie, Doyle Alysa E, Seidman Larry J, Faraone Stephen V
Pediatric Psychopharmacology and Adult ADHD Program, Psychiatry Department, Massachusetts General Hospital, Boston, Massachusetts 02114, USA.
J Nerv Ment Dis. 2007 Mar;195(3):240-6. doi: 10.1097/01.nmd.0000243968.06789.73.
One of the suspected sources of negative outcomes associated with attention-deficit/hyperactivity disorder (ADHD) has been a deficit in executive functions (EFD). Although self-report questionnaires purport to assess behavioral concomitants of EFDs, little is known about their informativeness. The aim was to examine the association between self-reported behavioral concomitants of EFDs and functional outcomes among adults with ADHD. Subjects were adults with (N = 200) and without (N = 138) DSM-IV criteria for ADHD. The Current Behavior Scale (CBS) was used as a proxy for EFDs. The 50th percentile of the ADHD subjects' total CBS scores explained the most variance in the functional outcomes compared with other cutoffs, and it identified subjects with more impaired global functioning, more comorbidities, and lower socioeconomic status. Scores on the CBS above the 50th percentile identify adults with ADHD at significantly higher risk for functional morbidity beyond that conferred by the diagnosis of ADHD alone.
与注意力缺陷多动障碍（ADHD）相关的负面结果的可疑来源之一是执行功能缺陷（EFD）。尽管自我报告问卷旨在评估EFD的行为伴随情况，但对其信息量了解甚少。目的是研究患有ADHD的成年人中自我报告的EFD行为伴随情况与功能结果之间的关联。研究对象为符合（N = 200）和不符合（N = 138）DSM-IV ADHD标准的成年人。使用当前行为量表（CBS）作为EFD的替代指标。与其他临界值相比，ADHD受试者CBS总分的第50百分位数在功能结果中解释的方差最大，并且它识别出整体功能受损更严重、合并症更多且社会经济地位较低的受试者。CBS得分高于第50百分位数表明，患有ADHD的成年人出现功能发病的风险显著高于仅由ADHD诊断所带来的风险。
