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骨质疏松性骨折:死亡率与生活质量

Osteoporotic fractures: mortality and quality of life.

作者信息

Caliri A, De Filippis L, Bagnato G L, Bagnato G F

机构信息

Unit of Rheumatology, Department of Internal Medicine, G. Martino Hospital, Messina, Italy.

出版信息

Panminerva Med. 2007 Mar;49(1):21-7.

Abstract

Osteoporosis is a widespread disease, affecting about 75 million people, mostly postmenopausal women. It is called ''the silent disease'', since there are very few associated symptoms: anyway osteoporotic fractures are the chief clinical feature, with an enormous burden on health related quality of life and mortality. The aim of this study was to review the literature on the evaluation of mortality and health related quality of life as consequences of osteoporotic fractures. Fractures, the clinical manifestation of osteoporosis, are extremely common and are devastating both to affected patients and to society that must bear the enormous cost of fracture treatment and subsequent disability. Hip and spine fractures are linked with increased mortality, and all fractures may lead to disability and reduced quality of life. Since patients with osteoporosis usually have no symptoms before fracture, early diagnosis and treatment of the disease are of great importance to the quality of life in these patients. To reduce mortality, attention must focus on optimising health status preoperatively, preventing postoperative complications, and, when these complications develop, providing optimal specialist medical care.

摘要

骨质疏松症是一种广泛存在的疾病,影响着约7500万人,其中大多数是绝经后女性。它被称为“无声的疾病”,因为与之相关的症状很少:无论如何,骨质疏松性骨折是主要的临床特征,对健康相关生活质量和死亡率造成巨大负担。本研究的目的是回顾关于评估骨质疏松性骨折所致死亡率和健康相关生活质量的文献。骨折作为骨质疏松症的临床表现极为常见,对受影响的患者以及必须承担骨折治疗和后续残疾巨大成本的社会都具有毁灭性。髋部和脊柱骨折与死亡率增加相关,所有骨折都可能导致残疾和生活质量下降。由于骨质疏松症患者在骨折前通常没有症状,因此该疾病的早期诊断和治疗对这些患者的生活质量至关重要。为降低死亡率,必须注重术前优化健康状况、预防术后并发症,以及在这些并发症发生时提供最佳的专科医疗护理。

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