7-巯基庚酰苏氨酸磷酸替代热稳定因子（可移动因子）以支持运动甲烷微菌的生长。

7-Mercaptoheptanoylthreonine phosphate substitutes for heat-stable factor (mobile factor) for growth of Methanomicrobium mobile.

作者信息

Kuhner C H, Smith S S, Noll K M, Tanner R S, Wolfe R S

机构信息

Department of Microbiology, University of Illinois, Urbana 61801.

出版信息

Appl Environ Microbiol. 1991 Oct;57(10):2891-5. doi: 10.1128/aem.57.10.2891-2895.1991.

DOI:10.1128/aem.57.10.2891-2895.1991

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC183892/

Abstract

Methanomicrobium mobile requires a heat-stable factor present in ruminal fluid and in boiled cell extract from Methanobacterium thermoautotrophicum for growth. By comparing the growth of M. mobile with boiled cell extract with that observed with various methanogenic cofactors, we found that 7-mercaptoheptanoylthreonine phosphate (HS-HTP) supported sustained growth of M. mobile, at an optimal concentration of 100 microM. No derivatives or possible biosynthetic precursors of HS-HTP could replace HS-HTP as the sole source of growth factor. Results suggest that the growth requirement might be satisfied by 7-mercaptoheptanoic acid plus a second, unidentified heat-stable factor.

摘要

活动甲烷微菌生长需要瘤胃液和嗜热自养甲烷杆菌煮沸细胞提取物中存在的一种热稳定因子。通过比较活动甲烷微菌与煮沸细胞提取物共同培养时的生长情况和与各种产甲烷辅助因子共同培养时的生长情况，我们发现7-巯基庚酰苏氨酸磷酸（HS-HTP）能支持活动甲烷微菌持续生长，最佳浓度为100微摩尔。HS-HTP的任何衍生物或可能的生物合成前体都不能替代HS-HTP作为唯一的生长因子来源。结果表明，7-巯基庚酸加上另一种未鉴定的热稳定因子可能满足生长需求。

相似文献

1

7-Mercaptoheptanoylthreonine phosphate substitutes for heat-stable factor (mobile factor) for growth of Methanomicrobium mobile.7-巯基庚酰苏氨酸磷酸替代热稳定因子（可移动因子）以支持运动甲烷微菌的生长。

Appl Environ Microbiol. 1991 Oct;57(10):2891-5. doi: 10.1128/aem.57.10.2891-2895.1991.

2

Evidence that the heterodisulfide of coenzyme M and 7-mercaptoheptanoylthreonine phosphate is a product of the methylreductase reaction in Methanobacterium.辅酶M与7-巯基庚酰苏氨酸磷酸的异二硫化物是甲烷杆菌中甲基还原酶反应产物的证据。

Biochem Biophys Res Commun. 1987 Dec 16;149(2):455-60. doi: 10.1016/0006-291x(87)90389-5.

3

The role of 7-mercaptoheptanoylthreonine phosphate in the methylcoenzyme M methylreductase system from Methanobacterium thermoautotrophicum.7-巯基庚酰苏氨酸磷酸在嗜热自养甲烷杆菌甲基辅酶M甲基还原酶系统中的作用。

Biochem Biophys Res Commun. 1987 May 29;145(1):204-10. doi: 10.1016/0006-291x(87)91307-6.

4

Synthesis of 7-mercaptoheptanoylthreonine phosphate and its activity in the methylcoenzyme M methylreductase system.

J Biol Chem. 1987 Jan 15;262(2):513-5.

5

Nutritional requirements of Methanomicrobium mobile.活动甲烷微菌的营养需求。

Appl Environ Microbiol. 1988 Mar;54(3):625-8. doi: 10.1128/aem.54.3.625-628.1988.

6

Biosynthesis of (7-mercaptoheptanoyl)threonine phosphate.（7-巯基庚酰基）磷酸苏氨酸的生物合成。

Biochemistry. 1994 Jun 14;33(23):7077-81. doi: 10.1021/bi00189a009.

7

7-Mercaptoheptanoylthreonine phosphate functions as component B in ATP-independent methane formation from methyl-CoM with reduced cobalamin as electron donor.

FEBS Lett. 1987 Mar 9;213(1):123-7. doi: 10.1016/0014-5793(87)81476-x.

8

Properties of the two isoenzymes of methyl-coenzyme M reductase in Methanobacterium thermoautotrophicum.嗜热自养甲烷杆菌中甲基辅酶M还原酶两种同工酶的性质

Eur J Biochem. 1993 Oct 15;217(2):587-95. doi: 10.1111/j.1432-1033.1993.tb18281.x.

9

Component C of the methylcoenzyme M methylreductase system contains bound 7-mercaptoheptanoylthreonine phosphate (HS-HTP).甲基辅酶M甲基还原酶系统的组分C含有结合的7-巯基庚酰苏氨酸磷酸（HS-HTP）。

Biochem Biophys Res Commun. 1986 Sep 30;139(3):889-95. doi: 10.1016/s0006-291x(86)80261-3.

10

Physiological importance of the heterodisulfide of coenzyme M and 7-mercaptoheptanoylthreonine phosphate in the reduction of carbon dioxide to methane in Methanobacterium.辅酶M与7-巯基庚酰苏氨酸磷酸的异二硫键在甲烷杆菌中将二氧化碳还原为甲烷过程中的生理重要性。

Proc Natl Acad Sci U S A. 1988 Jan;85(1):60-3. doi: 10.1073/pnas.85.1.60.

引用本文的文献

1

Evolving understanding of rumen methanogen ecophysiology.对瘤胃产甲烷菌生态生理学的认识不断发展。

Front Microbiol. 2023 Nov 6;14:1296008. doi: 10.3389/fmicb.2023.1296008. eCollection 2023.

本文引用的文献

1

The role of polyamines in the neutralization of bacteriophage deoxyribonucleic acid.多胺在噬菌体脱氧核糖核酸中和中的作用。

J Biol Chem. 1960 Mar;235:769-75.

2

A colorimetric method for determining low concentrations of mercaptans.一种测定低浓度硫醇的比色法。

Arch Biochem Biophys. 1958 Apr;74(2):443-50. doi: 10.1016/0003-9861(58)90014-6.

3

Coenzyme M: preparation and assay.

Methods Enzymol. 1980;67:545-52. doi: 10.1016/s0076-6879(80)67067-0.

4

Carbon dioxide reduction factor and methanopterin, two coenzymes required for CO2 reduction to methane by extracts of Methanobacterium.二氧化碳还原因子和甲蝶呤是甲烷杆菌提取物将二氧化碳还原为甲烷所需的两种辅酶。

J Biol Chem. 1983 Jun 25;258(12):7536-40.

5

Characterization of Methanobacterium mobilis, sp. n., isolated from the bovine rumen.从牛瘤胃中分离出的运动甲烷杆菌（新种）的特性

J Bacteriol. 1968 May;95(5):1943-51. doi: 10.1128/jb.95.5.1943-1951.1968.

6

Nutritional requirements of Methanomicrobium mobile.活动甲烷微菌的营养需求。

Appl Environ Microbiol. 1988 Mar;54(3):625-8. doi: 10.1128/aem.54.3.625-628.1988.

7

Physiological importance of the heterodisulfide of coenzyme M and 7-mercaptoheptanoylthreonine phosphate in the reduction of carbon dioxide to methane in Methanobacterium.辅酶M与7-巯基庚酰苏氨酸磷酸的异二硫键在甲烷杆菌中将二氧化碳还原为甲烷过程中的生理重要性。

Proc Natl Acad Sci U S A. 1988 Jan;85(1):60-3. doi: 10.1073/pnas.85.1.60.

8

Synthesis of 7-mercaptoheptanoylthreonine phosphate and its activity in the methylcoenzyme M methylreductase system.

J Biol Chem. 1987 Jan 15;262(2):513-5.

9

Steps in the conversion of alpha-ketosuberate to 7-mercaptoheptanoic acid in methanogenic bacteria.

Biochemistry. 1989 Nov 28;28(24):9417-23. doi: 10.1021/bi00450a026.

10

A novel biosynthesis of medium chain length alpha-ketodicarboxylic acids in methanogenic archaebacteria.产甲烷古细菌中中链长度α-酮二羧酸的一种新型生物合成途径。

Arch Biochem Biophys. 1989 May 1;270(2):691-7. doi: 10.1016/0003-9861(89)90552-3.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

文档翻译

学术文献翻译模型，支持多种主流文档格式。