Hyun Byung-Ryool, Chen Hongyu, Rey Diego A, Wise Frank W, Batt Carl A
Department of Food Science, Department of Biomedical Engineering, School of Applied and Engineering Physics, Cornell University, Ithaca, New York 14853, USA.
J Phys Chem B. 2007 May 24;111(20):5726-30. doi: 10.1021/jp068455j. Epub 2007 May 2.
A simple procedure for transferring PbS and PbSe quantum dots into water is presented, along with characterization of the resulting water-soluble quantum dots. The external surface of the water-soluble quantum dots include carboxylic groups, which will allow target-specific labeling of cells. As a first example, near-infrared fluorescence imaging of human colon cancer cells is demonstrated using these water-soluble near-infrared fluorophores.
本文介绍了一种将硫化铅和硒化铅量子点转移到水中的简单方法，以及对所得水溶性量子点的表征。水溶性量子点的外表面含有羧基，这将允许对细胞进行靶向特异性标记。作为第一个例子，使用这些水溶性近红外荧光团展示了人结肠癌细胞的近红外荧光成像。
