用于诊断围产期1型人类免疫缺陷病毒感染的超敏p24抗原检测法。
Ultrasensitive p24 antigen assay for diagnosis of perinatal human immunodeficiency virus type 1 infection.
作者信息
Fiscus Susan A, Wiener Jeffrey, Abrams Elaine J, Bulterys Marc, Cachafeiro Ada, Respess Richard A
机构信息
University of North Carolina at Chapel Hill, Department of Microbiology and Immunology, Chapel Hill, North Carolina, USA.
出版信息
J Clin Microbiol. 2007 Jul;45(7):2274-7. doi: 10.1128/JCM.00813-07. Epub 2007 May 2.
Abstract
We evaluated an ultrasensitive p24 antigen enzyme immunosorbent assay on 802 plasma specimens from 582 infants and children of 0 to 180 days of age. Overall sensitivity and specificity were 91.7% and 98.5%, respectively. After exclusion of infants of less than 7 days of age, the sensitivity and specificity were 93.7% and 98.3%, respectively.
摘要
我们对来自582名0至180日龄婴幼儿的802份血浆样本进行了超灵敏p24抗原酶免疫吸附测定。总体敏感性和特异性分别为91.7%和98.5%。排除7日龄以下的婴儿后，敏感性和特异性分别为93.7%和98.3%。
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