Tabori-Kraft Janne, Sørensen Merete Juul, Kaergaard Martin, Dalsgaard Søren, Thomsen Per Hove
Psychiatric Hospital for Children and Adolescents, Aarhus University Hospital, Harald Selmers vej 66, 8240, Risskov, Denmark.
Eur Child Adolesc Psychiatry. 2007 Aug;16(5):347-51. doi: 10.1007/s00787-006-0571-2. Epub 2007 May 2.
The purpose of this study was to investigate whether OPTAx, an objective measurement of hyperactivity, impulsivity and inattention can be used to measure the positive clinical effect of stimulants found in children with hyperkinetic disorder (HKD) or attention deficit disorder without hyperactivity.
A total of 22 boys and one girl, with ages ranging between 7-12 years, diagnosed with HKD or attention deficit disorder without hyperactivity and receiving treatment with stimulants were tested with OPTAx, with and without stimulants. The main parameters investigated were: displacement, area, accuracy, variability, errors of commission and errors of omission.
OPTAx showed a significant improvement on all parameters during stimulant treatment compared with no treatment. The improvement measured by OPTAx was supported by clinical assessment, which found that 95% of the children improved much or very much on the Clinical Global Assessment Scale during stimulant treatment.
The objective parameters of the OPTAx reflected the clinical improvement found in children with HKD or attention deficit disorder without hyperactivity during stimulant treatment. This suggests a greater role for objective measurements such as OPTAx in daily clinical practise.
本研究旨在调查OPTAx（一种用于测量多动、冲动和注意力不集中的客观方法）是否可用于衡量在患有多动障碍（HKD）或无多动的注意力缺陷障碍儿童中发现的兴奋剂的积极临床效果。
共有22名男孩和1名女孩，年龄在7至12岁之间，被诊断患有HKD或无多动的注意力缺陷障碍且正在接受兴奋剂治疗，分别在服用和未服用兴奋剂的情况下接受了OPTAx测试。研究的主要参数包括：位移、面积、准确性、变异性、操作误差和遗漏误差。
与未治疗相比，OPTAx显示在兴奋剂治疗期间所有参数都有显著改善。OPTAx测量的改善得到了临床评估的支持，临床评估发现95%的儿童在兴奋剂治疗期间在临床总体评定量表上有很大或非常大的改善。
OPTAx的客观参数反映了患有HKD或无多动的注意力缺陷障碍儿童在兴奋剂治疗期间的临床改善情况。这表明诸如OPTAx之类的客观测量方法在日常临床实践中具有更大的作用。
