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疼痛评估在痴呆患者镇痛治疗中的应用

The utility of pain assessment for analgesic use in persons with dementia.

作者信息

Cohen-Mansfield Jiska, Lipson Steven

机构信息

Charles E. Smith Life Communities, Research Institute on Aging, 6121 Montrose Road, Rockville, MD 20852, USA.

出版信息

Pain. 2008 Jan;134(1-2):16-23. doi: 10.1016/j.pain.2007.03.023. Epub 2007 May 3.

Abstract

Ameliorating pain symptoms in persons with severe dementia is difficult due to the inherent problems of pain assessment and communication with this population. This study aims to examine the utility of nine pain assessments in identifying pain and documenting responsiveness to pain medication in 121 nursing home residents with dementia. The assessments included self-report, informant ratings by nursing staff, and direct observations. This was an open medication study, with comparison groups of persons with dementia. Those evaluated as having pain were included in the pain medication protocol. Three comparison groups were utilized: those not considered in pain at baseline, those in pain at baseline for whom caregivers refused to follow the pain medication protocol, and a subset of those not in pain at baseline who were followed for a period of time similar in length to the treatment group. Informant ratings were the assessments most likely to detect pain and direct observations were least likely to do so. Both self-report and informant ratings showed a significantly greater decrease in pain in the treatment group relative to the comparison groups. All participants who followed the pain protocol reached a pain free stage by the study criteria. A limitation of the study was the reduced endpoint number due to family or physician resistance to following treatment recommendations. The results present a methodology that caregivers can use to increase the detection of pain in persons with dementia, enabling them to treat it more effectively, and thereby improve life quality for dementia patients.

摘要

由于疼痛评估以及与重度痴呆患者沟通方面存在固有问题,改善这类患者的疼痛症状十分困难。本研究旨在检验九种疼痛评估方法在识别121名患有痴呆症的养老院居民的疼痛情况以及记录其对止痛药物反应方面的效用。这些评估方法包括自我报告、护理人员的知情者评分以及直接观察。这是一项开放性药物研究,设有痴呆症患者对照组。被评估为疼痛的患者纳入止痛药物方案。使用了三个对照组:基线时未被认为疼痛的患者、基线时疼痛但其护理人员拒绝遵循止痛药物方案的患者,以及基线时未疼痛且随访时间与治疗组相似的部分患者。知情者评分是最有可能检测到疼痛的评估方法,而直接观察则最不容易检测到疼痛。自我报告和知情者评分均显示,治疗组的疼痛程度相对于对照组有显著更大幅度的减轻。所有遵循止痛方案的参与者根据研究标准均达到无痛阶段。该研究的一个局限性是由于家属或医生抵制遵循治疗建议,导致终点数量减少。研究结果提出了一种方法,护理人员可利用该方法提高对痴呆症患者疼痛的检测能力,使其能够更有效地进行治疗,从而改善痴呆症患者的生活质量。

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