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一种基于改进形态学滤波器的脑电图尖峰检测方法。

A spike detection method in EEG based on improved morphological filter.

作者信息

Xu Guanghua, Wang Jing, Zhang Qing, Zhang Sicong, Zhu Junming

机构信息

State Key Laboratory for Manufacturing Systems Engineering, Xi'an Jiaotong University, Xi'an 710049, PR China.

出版信息

Comput Biol Med. 2007 Nov;37(11):1647-52. doi: 10.1016/j.compbiomed.2007.03.005. Epub 2007 May 7.

Abstract

In this paper, a spike detection method is introduced. Traditional morphological filter is improved for extracting spikes from epileptic EEG signals and two key problems are addressed: morphological operation design and structure elements optimization. An average weighted combination of open-closing and close-opening operation, which can eliminate statistical deflection of amplitude, is utilized to separate background EEG and spikes. Then, according to the characteristic of spike component, the structure elements are constructed with two parabolas and a new criterion is put forward to optimize the structure elements. The proposed method is evaluated using normal and epileptic EEG data recorded from 12 test subjects. A comparison between the improved morphological filter, traditional morphological filter and wavelet analysis with Mexican hat function is presented, which indicates that the improved morphological filter is superior in restraining background activities. We demonstrate that the average detection rate of the improved morphological filter is much higher than that of the other two methods, and there is no false detection for normal EEG signals with the proposed method.

摘要

本文介绍了一种尖峰检测方法。对传统形态滤波器进行了改进,以从癫痫脑电信号中提取尖峰,并解决了两个关键问题:形态运算设计和结构元素优化。利用开闭运算和闭开运算的平均加权组合来消除幅度的统计偏差,以分离背景脑电和尖峰。然后,根据尖峰成分的特征,用两条抛物线构造结构元素,并提出了一种新的准则来优化结构元素。使用从12名测试对象记录的正常和癫痫脑电数据对所提出的方法进行了评估。给出了改进的形态滤波器、传统形态滤波器和墨西哥帽函数小波分析之间的比较,这表明改进的形态滤波器在抑制背景活动方面更具优势。我们证明,改进的形态滤波器的平均检测率远高于其他两种方法,并且所提出的方法对正常脑电信号没有误检测。

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