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绝经后妇女接受卵母细胞捐赠后的连续妊娠。

Consecutive pregnancies in a menopausal woman following oocyte donation.

作者信息

Sauer M V, Paulson R J

机构信息

Department of Obstetrics and Gynecology, University of Southern California School of Medicine, Los Angeles.

出版信息

Gynecol Obstet Invest. 1991;32(2):118-20. doi: 10.1159/000293009.

Abstract

A second pregnancy was successfully achieved by a menopausal women who had previously conceived and delivered an infant using donated oocytes. The same nonanonymous oocyte donor provided the gametes for both procedures. Prior to embryo transfer, the functionally agonadal recipient received exogenous steroid hormone replacement therapy. Both pregnancies followed the transfer of 5 embryos which were conceived by the in vitro fertilization of the donated oocytes with the recipient husband's sperm. The first pregnancy ended with an intrauterine fetal demise at 40 weeks gestation. The second pregnancy is proceeding unremarkably.

摘要

一名绝经后妇女成功实现了第二次怀孕,她此前曾使用捐赠的卵母细胞受孕并分娩了一名婴儿。同一位非匿名卵母细胞捐赠者为这两次手术提供了配子。在胚胎移植前,功能上无性腺的受者接受了外源性类固醇激素替代疗法。两次怀孕均是在将5个胚胎移植后发生的,这些胚胎是由捐赠的卵母细胞与受者丈夫的精子进行体外受精而形成的。第一次怀孕在妊娠40周时以宫内胎儿死亡告终。第二次怀孕进展顺利。

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