Sakthi Kumar D, Fujioka Masayori, Asano Kentaro, Shoji Atsumu, Jayakrishnan Athipettah, Yoshida Yasuhiko
REDS Group, Saitama Small Enterprise Promotion Corporation, SKIP City, Kawaguchi, Japan.
J Mater Sci Mater Med. 2007 Sep;18(9):1831-5. doi: 10.1007/s10856-007-3033-6. Epub 2007 May 5.
Poly(ethylene glycol) (PEG) was 'polymerized' onto poly(ethylene terephthalate) (PET) surface by radio frequency (RF) plasma polymerization of PEG (average molecular weight 200 Da) at a monomer vapour partial pressure of 10 Pa. Thin films strongly adherent onto PET could be produced by this method. The modified surface was characterized by infra red (IR) spectroscopy, scanning electron microscopy (SEM), atomic force microscopy (AFM), cross-cut test, contact angle measurements and static platelet adhesion studies. The modified surface, believed to be extensively cross-linked, however showed all the chemical characteristics of PEG. The surface was found to be highly hydrophilic as evidenced by an interfacial free energy of about 0.7 dynes/cm. AFM studies showed that the surface of the modified PET became smooth by the plasma polymerized deposition. Static platelet adhesion studies using platelet rich plasma (PRP) showed considerably reduced adhesion of platelets onto the modified surface by SEM. Plasma 'polymerization' of a polymer such as PEG onto substrates may be a novel and interesting strategy to prepare PEG-like surfaces on a variety of substrates since the technique allows the formation of thin, pin-hole free, strongly adherent films on a variety of substrates.
通过在10 Pa的单体蒸汽分压下对聚乙二醇（PEG，平均分子量200 Da）进行射频（RF）等离子体聚合，将聚乙二醇（PEG）“聚合”到聚对苯二甲酸乙二酯（PET）表面。通过这种方法可以制备出牢固附着在PET上的薄膜。通过红外（IR）光谱、扫描电子显微镜（SEM）、原子力显微镜（AFM）、划格试验、接触角测量和静态血小板黏附研究对改性表面进行了表征。改性表面被认为是广泛交联的，但却显示出PEG的所有化学特征。通过约0.7达因/厘米的界面自由能证明该表面具有高度亲水性。AFM研究表明，经等离子体聚合沉积后，改性PET的表面变得光滑。使用富血小板血浆（PRP）进行的静态血小板黏附研究表明，通过SEM观察到血小板在改性表面上的黏附显著减少。将诸如PEG之类的聚合物通过等离子体“聚合”到基底上可能是一种在各种基底上制备类PEG表面的新颖且有趣的策略，因为该技术能够在各种基底上形成薄的、无针孔的、牢固附着的薄膜。
