Konuk Numan, Koca Rafet, Atik Levent, Muhtar Sennur, Atasoy Nuray, Bostanci Bora
Department of Psychiatry, Faculty of Medicine, Zonguldak Karaelmas University, Kozlu/Zonguldak, Turkey.
Gen Hosp Psychiatry. 2007 May-Jun;29(3):232-5. doi: 10.1016/j.genhosppsych.2007.01.006.
Psychogenic factors may play a contributory role in the development or persistence of lichen simplex chronicus (LSC). The objective of this study was to evaluate the psychiatric profile of patients with LSC including depression and dissociative experiences.
Dermatology outpatients with a LSC (n=30) were compared with outpatients with tinea in which psychological factors are regarded as negligible (n=30). All subjects were given psychiatric scales including the Symptom Checklist-90-Revised (SCL-90-R), Hamilton Rating Scale for Depression (HAM-D) and Dissociative Experience Scale (DES).
All mean SCL-90 scores for general psychopathology were higher in the LSC compared to the control group. HAM-D and DES scores were significantly higher in the LSC group (P<.05) as well. In addition, the number of patients whose total DES score of 30 and above was higher in the LSC group.
Psychiatric symptoms appear relatively common among patients with LSC. Further research is needed to confirm the possible role of dissociative tendencies in the etiology of LSC.
心理因素可能在慢性单纯性苔藓(LSC)的发生或持续存在中起促成作用。本研究的目的是评估LSC患者的精神状况,包括抑郁和分离体验。
将30例LSC皮肤科门诊患者与30例心理因素可忽略不计的股癣门诊患者进行比较。所有受试者均接受精神科量表评估,包括症状自评量表-90修订版(SCL-90-R)、汉密尔顿抑郁量表(HAM-D)和分离体验量表(DES)。
与对照组相比,LSC组所有一般精神病理学的SCL-90平均得分更高。LSC组的HAM-D和DES得分也显著更高(P<0.05)。此外,DES总分在30分及以上的患者数量在LSC组中更多。
精神症状在LSC患者中似乎相对常见。需要进一步研究以证实分离倾向在LSC病因学中可能发挥的作用。