Bader Michael, Zimmer Holger, Triebig Gerhard
Hannover Medical School, Department of Occupational Medicine, Hannover, Germany.
Ind Health. 2007 Apr;45(2):338-42. doi: 10.2486/indhealth.45.338.
Pentachlorophenol (PCP) was widely used as a wood preservative in Germany until 1989, when it was prohibited by law. Within a cross-sectional study we investigated the internal PCP exposure of painters and bricklayers between one year and four years after the ban. PCP was analysed in post-shift urine samples of 189 painters and 148 bricklayers by gas chromatography and electron capture detection (GC-ECD). The median PCP concentration in the urine of painters was 2.4 microg/g creatinine (range: 0.2-52 microg/g creatinine). For the bricklayers a range of 0.1-25 microg/g creatinine (median: 1.8 microg/g creatinine) was determined. The difference between both groups was statistically significant, pointing to a small additional uptake of PCP by the painters probably from an exposure to contaminated wood surfaces or residual PCP containing preservatives. The biomonitoring results for both groups coincided with background values of the general population at that time.
直到1989年被法律禁止之前，五氯苯酚（PCP）在德国被广泛用作木材防腐剂。在一项横断面研究中，我们调查了禁令实施一年至四年后油漆工和泥瓦匠体内PCP的暴露情况。通过气相色谱和电子捕获检测（GC-ECD）分析了189名油漆工和148名泥瓦匠轮班后的尿液样本中的PCP。油漆工尿液中PCP的中位数浓度为2.4微克/克肌酐（范围：0.2 - 52微克/克肌酐）。泥瓦匠的PCP浓度范围为0.1 - 25微克/克肌酐（中位数：1.8微克/克肌酐）。两组之间的差异具有统计学意义，表明油漆工可能因接触受污染的木材表面或含PCP的残留防腐剂而额外少量摄入了PCP。两组的生物监测结果与当时普通人群的背景值相符。
