Pirzada S, Tomi Z, Gulliver W
Dalhousie University, Halifax, Canada.
Skin Therapy Lett. 2007 Apr;12(3):1-4.
Moderate-to-severe psoriasis is known to affect millions of people around the globe. This chronic disease substantially impacts patients by impairing their quality of life, causing psychosocial distress, and creating an ongoing financial burden. The biologics are the newest and most effective therapeutic weapon in the treatment of moderate-to-severe psoriasis and psoriatic arthritis that can significantly alter the course of the disease in a relatively short period of time. There is a need to review the recommended treatment guidelines for moderate- to-severe psoriasis and psoriatic arthritis as the perception and demands of patients are constantly changing. Real world experience with this class of drugs is expanding and more new biologics are becoming available.
众所周知，中重度银屑病影响着全球数百万人。这种慢性病严重影响患者的生活质量，造成心理社会困扰，并带来持续的经济负担。生物制剂是治疗中重度银屑病和银屑病关节炎的最新、最有效的治疗手段，能在相对较短的时间内显著改变疾病进程。由于患者的认知和需求不断变化，有必要对中重度银屑病和银屑病关节炎的推荐治疗指南进行审查。这类药物的真实世界经验正在不断扩展，越来越多的新型生物制剂可供使用。
