Kragballe Knud, Deleuran Bent
Arhus Universitetshospital, Arhus Sygehus, Dermatologisk Afdeling S.
Ugeskr Laeger. 2008 Jun 9;170(24):2148-50.
Psoriasis is an immune-mediated inflammatory skin disease which may be associated with psoriatic arthritis. Biological therapy is indicated in patients who do not respond to, or are intolerant to, or have contraindication against traditional therapy. TNFalpha antagonists are used for both skin and joint disease, while efalizumab, which targets T lymphocytes, is only indicated for the skin disease. Registration of the treated patients in quality databases is an essential instrument in the surveillance of beneficial and adverse events during biological therapy.
银屑病是一种免疫介导的炎症性皮肤病，可能与银屑病关节炎相关。对于那些对传统治疗无反应、不耐受或有禁忌的患者，可采用生物疗法。肿瘤坏死因子α拮抗剂可用于治疗皮肤和关节疾病，而针对T淋巴细胞的依法利珠单抗仅用于治疗皮肤病。将接受治疗的患者纳入质量数据库进行登记，是监测生物治疗期间有益和不良事件的重要手段。
