Fiorino Francesco, Barbieri Franco
Department of Otolaryngology, Civil Hospital Borgo Trento, Verona, Italy.
Eur Arch Otorhinolaryngol. 2007 Oct;264(10):1125-8. doi: 10.1007/s00405-007-0323-z. Epub 2007 May 9.
The objective of the present study was to evaluate the efficacy of fat graft myringoplasty in repairing residual or recurrent tympanic membrane perforation. A retrospective analysis was performed on 31 patients, aged 25-57 years (mean 43.3), submitted to myringoplasty revision using fat graft. Fourteen were males and 17 females. Perforation size ranged from 1 to 5 mm. Follow-up time ranged from 4 to 62 months (mean 26 months). Fat graft myringoplasty was performed under local anesthesia, using ear lobe fat in 26 patients and abdominal fat in five patients closure of tympanic membrane perforation was achieved in 87.1% of ears. No modification of the hearing level was evidenced at the statistical analysis. Fat graft myringoplasty is a safe, effective and minimally invasive procedure, suitable to repair small residual/recurrent perforations of the tympanic membrane. The angiogenic properties of the fat are ideal to overcome the poor vascular supply in the vicinity of the tympanic membrane perforation.
本研究的目的是评估脂肪移植鼓膜成形术修复残余或复发性鼓膜穿孔的疗效。对31例年龄在25 - 57岁（平均43.3岁）接受脂肪移植鼓膜成形术翻修的患者进行回顾性分析。其中男性14例，女性17例。穿孔大小为1至5毫米。随访时间为4至62个月（平均26个月）。脂肪移植鼓膜成形术在局部麻醉下进行，26例患者使用耳垂脂肪，5例患者使用腹部脂肪。87.1%的耳实现了鼓膜穿孔闭合。统计学分析未发现听力水平有改变。脂肪移植鼓膜成形术是一种安全、有效且微创的手术方法，适用于修复鼓膜小的残余/复发性穿孔。脂肪的血管生成特性非常适合克服鼓膜穿孔附近血管供应不足的问题。
