大麻使用和大量饮酒对俄罗斯海洛因使用者中艾滋病毒药物风险行为的影响。
Implications of cannabis use and heavy alcohol use on HIV drug risk behaviors in Russian heroin users.
作者信息
Walley Alexander Y, Krupitsky Evgeny M, Cheng Debbie M, Raj Anita, Edwards Erika M, Bridden Carly, Egorova Valentina Y, Zvartau Edwin E, Woody George E, Samet Jeffrey H
机构信息
Clinical Addiction Research and Education Unit, Section of General Internal Medicine, Department of Medicine, Boston Medical Center and Boston University School of Medicine, 91 E. Concord St., Suite 200, Boston, MA 02118, USA.
出版信息
AIDS Behav. 2008 Jul;12(4):662-9. doi: 10.1007/s10461-007-9243-6. Epub 2007 May 9.
Cannabis and heavy alcohol use potentially increase HIV transmission by increasing risky drug behaviors. We studied 404 subjects entering treatment for heroin dependence, in St. Petersburg, Russia. We used the HIV Risk Assessment Battery (RAB) drug subscale to measure risky drug behavior. Although all heavy alcohol users had risky drug behaviors, their drug RAB scores did not differ from non-heavy alcohol users in unadjusted or adjusted analyses. Cannabis use was significantly associated with drug RAB scores in unadjusted analyses (mean difference 1.7 points) and analyses adjusted for age, sex, and employment (mean difference 1.3 points). When also adjusting for stimulant use, the impact of cannabis use was attenuated and no longer statistically significant (mean difference 1.1 points). Because of the central role of risky drug behaviors in the Russian HIV epidemic, it is important to understand how the use of multiple substances, including cannabis and alcohol, impacts risky drug behaviors.
大麻和大量饮酒可能会通过增加危险的吸毒行为来提高艾滋病毒的传播率。我们对俄罗斯圣彼得堡404名因海洛因依赖而接受治疗的受试者进行了研究。我们使用了艾滋病毒风险评估量表（RAB）中的毒品分量表来衡量危险的吸毒行为。尽管所有大量饮酒者都有危险的吸毒行为，但在未经调整或调整后的分析中，他们的毒品RAB得分与非大量饮酒者并无差异。在未经调整的分析中（平均差异1.7分）以及在对年龄、性别和就业情况进行调整后的分析中（平均差异1.3分），大麻使用与毒品RAB得分显著相关。当同时对兴奋剂使用情况进行调整时，大麻使用的影响减弱，不再具有统计学意义（平均差异1.1分）。鉴于危险的吸毒行为在俄罗斯艾滋病毒流行中所起的核心作用，了解包括大麻和酒精在内的多种物质的使用如何影响危险的吸毒行为非常重要。
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