Gombos Katalin, Jakubovits Edit, Kolos Agoston, Salacz György, Németh Janos
Department of Ophthalmology, Semmelweis University, Budapest, Hungary.
Acta Ophthalmol Scand. 2007 May;85(3):309-16. doi: 10.1111/j.1600-0420.2007.00924.x.
To compare the effectiveness for the patient of retrobulbar anaesthesia (RBA) and topical anaesthesia (TA) in cataract surgery by phacoemulsification.
We performed a prospective, randomized study on 115 patients operated at our clinic using the two anaesthesia techniques. The RBA group comprised 57 patients (20 women, 37 men; age 72 +/- 10 years); the TA group comprised 58 patients (20 women, 38 men; age 74 +/- 10 years). Measured parameters were: blood pressure; heart rate; blood oxygen saturation level; serum adrenaline, noradrenaline and cortisol levels; white blood cell count; indicated pain during the procedure, and pain as reported by the patient afterwards. Two psychological tests were used: the State-Trait Anxiety Inventory (STAI), and the patient-selected face-scale test. Statistical analysis was performed using Student's t-test and the chi-square test. Results were also analysed using a logistic regression model.
Both types of anaesthesia were adequate for the surgical procedure. In the RBA group fewer patients experienced pain during surgery (p < 0.01) and fewer recalled any perioperative discomfort. With RBA the objective parameters were more stable than with TA, and systolic blood pressure was significantly lower (p = 0.01). The logistic model was able to predict perioperative pain with 93% certainty. Pain sensitivity was higher in younger patients and in patients with higher initial cortisol and noradrenaline serum levels.
Both methods of anaesthesia are appropriate, but phacoemulsification with TA is more painful than with RBA. In hypertonic patients and younger patients who are more susceptible to pain, TA should be avoided or used in combination with individualized sedation.
比较球后麻醉(RBA)和表面麻醉(TA)在白内障超声乳化手术中对患者的效果。
我们对在本诊所采用这两种麻醉技术进行手术的115例患者进行了一项前瞻性随机研究。RBA组包括57例患者(20名女性,37名男性;年龄72±10岁);TA组包括58例患者(20名女性,38名男性;年龄74±10岁)。测量参数包括:血压、心率、血氧饱和度水平、血清肾上腺素、去甲肾上腺素和皮质醇水平、白细胞计数、术中指示疼痛以及患者术后报告的疼痛。使用了两项心理测试:状态-特质焦虑量表(STAI)和患者选择的面部量表测试。采用学生t检验和卡方检验进行统计分析。结果也使用逻辑回归模型进行分析。
两种麻醉方式均足以满足手术过程。RBA组术中经历疼痛的患者较少(p<0.01),术后回忆起任何围手术期不适的患者也较少。与TA相比,RBA时客观参数更稳定,收缩压显著更低(p = 0.01)。逻辑模型能够以93%的确定性预测围手术期疼痛。年轻患者以及初始皮质醇和去甲肾上腺素血清水平较高的患者疼痛敏感性更高。
两种麻醉方法均适用,但TA下的超声乳化手术比RBA更疼痛。对于高渗患者和对疼痛更敏感的年轻患者,应避免使用TA或与个体化镇静联合使用。