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地中海贫血服务作为遗传学服务成本效益分析的一个范例

Services for thalassaemia as a model for cost-benefit analysis of genetics services.

作者信息

Modell B, Kuliev A M

机构信息

Department of Obstetrics and Gynaecology, UCMSM, University College, London, UK.

出版信息

J Inherit Metab Dis. 1991;14(4):640-51. doi: 10.1007/BF01797934.

DOI:10.1007/BF01797934
PMID:1749229
Abstract

Economic appraisal of genetics services is usually limited to consideration of financial costs and benefits, but this can generate misunderstandings about the aims of these services. We propose a general framework for economic analysis that includes non-financial costs and benefits, and the concept of genetic fitness.

摘要

遗传学服务的经济评估通常局限于对财务成本和收益的考量,但这可能会引发对这些服务目标的误解。我们提出了一个经济分析的通用框架,其中包括非财务成本和收益,以及遗传适应性的概念。

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Services for thalassaemia as a model for cost-benefit analysis of genetics services.地中海贫血服务作为遗传学服务成本效益分析的一个范例
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Hum Reprod. 2011 May;26(5):972-7. doi: 10.1093/humrep/der042. Epub 2011 Feb 28.
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Response to: What counts as success in genetic counselling?对《基因咨询中的成功标准是什么?》的回应
J Med Ethics. 1993 Mar;19(1):47-9. doi: 10.1136/jme.19.1.47.
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Prenatal screening for cystic fibrosis carriers: an economic evaluation.囊性纤维化携带者的产前筛查:一项经济学评估。

本文引用的文献

1
Effect of introducing antenatal diagnosis on reproductive behaviour of families at risk for thalassaemia major.引入产前诊断对重型地中海贫血高危家庭生殖行为的影响。
Br Med J. 1980 Jun 7;280(6228):1347-50. doi: 10.1136/bmj.280.6228.1347.
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Management of thalassaemia major.重型地中海贫血的管理
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Cost-benefit analysis of a thalassemia disease prevention program.地中海贫血疾病预防项目的成本效益分析。
Am J Public Health. 1985 Jul;75(7):732-6. doi: 10.2105/ajph.75.7.732.
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First-trimester fetal diagnosis for haemoglobinopathies: report on 200 cases.
Lancet. 1986 Oct 4;2(8510):763-7. doi: 10.1016/s0140-6736(86)90296-5.
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Prenatal diagnosis and genetic screening. Community and service implications. Summary and recommendations of a report of the Royal College of Physicians.产前诊断与基因筛查。对社区及服务的影响。皇家内科医师学院一份报告的总结与建议。
J R Coll Physicians Lond. 1989 Oct;23(4):215-20.
9
An economic appraisal of screening for Down's syndrome in pregnancy using maternal age and serum alpha fetoprotein concentration.利用孕妇年龄和血清甲胎蛋白浓度对孕期唐氏综合征筛查进行的经济学评估。
Soc Sci Med. 1987;24(9):725-31. doi: 10.1016/0277-9536(87)90109-2.
10
Preventing the birth of infants with Down's syndrome: a cost-benefit analysis.预防唐氏综合征婴儿的出生:成本效益分析。
Br Med J. 1976 Mar 27;1(6012):753-6. doi: 10.1136/bmj.1.6012.753.