Milojković M, Lederer B, Jarcov R, Pajtler M
Odjel za ginekologiju i porodiljstvo i Odjel za klinicku citologiju Opće bolnice Osijek.
Jugosl Ginekol Perinatol. 1991 May-Aug;31(3-4):99-101.
In the period from 1985 to 1989, 2521 pregnant women, making up 18.7% of women in fertile age, were controlled in antenatal surgeries in the area of Baranja. In 73 (2.9%) women a cytologic picture of cervical atypia was found: in 2.1% of them there was a cytologic picture of light and moderate dysplasia (group IIIA), in 0.6% a picture of severe dysplasia (group IIIB), and in 0.2% pregnant women there was a picture of carcinoma in situ (group IV). Progression of cytologic findings into a higher stage was noted in 23.3% women, persistence was recorded in 21.9% and regression in 54.8% women. A total of 71.2% pregnant women with the cytologic atypia of the cervix were colposcopically examined. An abnormal colposcopic picture was found in 65.4% of them. By the end of the puerperium histologic verification was made in 38.4% cases and 61.6% were controlled only cytologically and colposcopically. By means of histologic examination of the tissue specimen, progression of an intraepithelial lesion into an invasive carcinoma was not found in any of the women. These results corroborate the point of view that in pregnant women with the cytologic atypia of the uterine cervix the histologic verification can be postponed until after the delivery without any considerable risk. Only in the case of a cytologic or colposcopic suspicion of invasion it is necessary to verify the finding histologically.
1985年至1989年期间，在巴拉尼亚地区，2521名孕妇接受了产前检查，占育龄妇女的18.7%。73名（2.9%）妇女宫颈出现非典型细胞学表现：其中2.1%为轻度和中度发育异常的细胞学表现（ⅢA组），0.6%为重度发育异常（ⅢB组），0.2%的孕妇为原位癌（Ⅳ组）。23.3%的妇女细胞学检查结果进展至更高阶段，21.9%持续存在，54.8%出现消退。共有71.2%宫颈细胞学非典型的孕妇接受了阴道镜检查。其中65.4%发现阴道镜图像异常。产褥期末，38.4%的病例进行了组织学检查，61.6%仅进行了细胞学和阴道镜检查。通过组织标本的组织学检查，未发现任何妇女的上皮内病变进展为浸润癌。这些结果证实了这样一种观点，即对于宫颈细胞学非典型的孕妇，组织学检查可推迟至分娩后进行，而不会有任何重大风险。只有在细胞学或阴道镜怀疑有浸润的情况下，才需要进行组织学检查以证实诊断。
