Reeder C B, Connolly S M, Winkelmann R K
Division of Hematology/Oncology, Mayo Clinic Scottsdale, AZ 85259.
Mayo Clin Proc. 1991 Dec;66(12):1222-4. doi: 10.1016/s0025-6196(12)62473-2.
We describe a woman in whom hypogammaglobulinemia and severe granulomatous cutaneous lesions had developed during childhood; subsequently, Hodgkin's disease and necrobiotic xanthogranuloma were diagnosed. This case illustrates an apparent association with disease activity and raises the question of a direct relationship of necrobiotic xanthogranuloma with lymphoproliferative disease.
我们描述了一名女性，她在儿童时期出现了低丙种球蛋白血症和严重的肉芽肿性皮肤病变；随后，被诊断出患有霍奇金病和渐进性坏死性黄色肉芽肿。该病例说明了与疾病活动的明显关联，并提出了渐进性坏死性黄色肉芽肿与淋巴增殖性疾病之间直接关系的问题。
