Gallucci Massimo, Limbucci Nicola, Paonessa Amalia, Splendiani Alessandra
Department of Radiology, University of L'Aquila, S. Salvatore Hospital, Via Vetoio, Loc. Coppito, 67100 L'Aquila, Italy.
Neuroimaging Clin N Am. 2007 Feb;17(1):87-103. doi: 10.1016/j.nic.2007.01.002.
Degenerative disease of the spine is a definition that includes a wide spectrum of degenerative abnormalities. Degeneration involves bony structures and the intervertebral disk, although many aspects of spine degeneration are strictly linked because the main common pathogenic factor is identified in chronic overload. During life the spine undergoes continuous changes as a response to physiologic axial load. These age-related changes are similar to pathologic degenerative changes and are a common asymptomatic finding in adults and elderly persons. A mild degree of degenerative changes is paraphysiologic and should be considered pathologic only if abnormalities determine symptoms. Imaging allows complete evaluation of static and dynamic factors related to degenerative disease of the spine and is useful in diagnosing the different aspects of spine degeneration.
脊柱退行性疾病是一个涵盖广泛退行性异常的定义。退变涉及骨结构和椎间盘，尽管脊柱退变的许多方面紧密相连，因为主要的共同致病因素是慢性负荷。在生命过程中，脊柱会作为对生理性轴向负荷的反应而持续发生变化。这些与年龄相关的变化类似于病理性退变变化，是成年人和老年人常见的无症状表现。轻度的退变变化是准生理性的，只有当异常导致症状时才应被视为病理性的。影像学检查能够全面评估与脊柱退行性疾病相关的静态和动态因素，有助于诊断脊柱退变的不同方面。
