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肺康复:美国胸科医师学会/美国心血管和肺康复协会基于证据的联合临床实践指南

Pulmonary Rehabilitation: Joint ACCP/AACVPR Evidence-Based Clinical Practice Guidelines.

作者信息

Ries Andrew L, Bauldoff Gerene S, Carlin Brian W, Casaburi Richard, Emery Charles F, Mahler Donald A, Make Barry, Rochester Carolyn L, Zuwallack Richard, Herrerias Carla

机构信息

University of California, San Diego, Department of Pulmonary and Critical Care Medicine, UCSD Medical Center, 200 West Arbor Dr, San Diego, CA 92103-8377, USA.

出版信息

Chest. 2007 May;131(5 Suppl):4S-42S. doi: 10.1378/chest.06-2418.

Abstract

BACKGROUND

Pulmonary rehabilitation has become a standard of care for patients with chronic lung diseases. This document provides a systematic, evidence-based review of the pulmonary rehabilitation literature that updates the 1997 guidelines published by the American College of Chest Physicians (ACCP) and the American Association of Cardiovascular and Pulmonary Rehabilitation.

METHODS

The guideline panel reviewed evidence tables, which were prepared by the ACCP Clinical Research Analyst, that were based on a systematic review of published literature from 1996 to 2004. This guideline updates the previous recommendations and also examines new areas of research relevant to pulmonary rehabilitation. Recommendations were developed by consensus and rated according to the ACCP guideline grading system.

RESULTS

The new evidence strengthens the previous recommendations supporting the benefits of lower and upper extremity exercise training and improvements in dyspnea and health-related quality-of-life outcomes of pulmonary rehabilitation. Additional evidence supports improvements in health-care utilization and psychosocial outcomes. There are few additional data about survival. Some new evidence indicates that longer term rehabilitation, maintenance strategies following rehabilitation, and the incorporation of education and strength training in pulmonary rehabilitation are beneficial. Current evidence does not support the routine use of inspiratory muscle training, anabolic drugs, or nutritional supplementation in pulmonary rehabilitation. Evidence does support the use of supplemental oxygen therapy for patients with severe hypoxemia at rest or with exercise. Noninvasive ventilation may be helpful for selected patients with advanced COPD. Finally, pulmonary rehabilitation appears to benefit patients with chronic lung diseases other than COPD.

CONCLUSIONS

There is substantial new evidence that pulmonary rehabilitation is beneficial for patients with COPD and other chronic lung diseases. Several areas of research provide opportunities for future research that can advance the field and make rehabilitative treatment available to many more eligible patients in need.

摘要

背景

肺康复已成为慢性肺部疾病患者的标准治疗方法。本文献对肺康复文献进行了系统的、基于证据的综述,更新了美国胸科医师学会(ACCP)和美国心血管与肺康复协会于1997年发布的指南。

方法

指南小组审查了由ACCP临床研究分析师编制的证据表,这些证据表基于对1996年至2004年发表文献的系统综述。本指南更新了先前的建议,并探讨了与肺康复相关的新研究领域。建议通过共识制定,并根据ACCP指南分级系统进行评级。

结果

新证据强化了先前的建议,即支持下肢和上肢运动训练的益处,以及肺康复在改善呼吸困难和与健康相关的生活质量方面的效果。更多证据支持在医疗保健利用和心理社会结局方面的改善。关于生存率的额外数据较少。一些新证据表明,长期康复、康复后的维持策略以及在肺康复中纳入教育和力量训练是有益的。目前的证据不支持在肺康复中常规使用吸气肌训练、合成代谢药物或营养补充剂。证据支持对静息时或运动时严重低氧血症患者使用补充氧气疗法。无创通气可能对某些晚期慢性阻塞性肺疾病(COPD)患者有帮助。最后,肺康复似乎对COPD以外的慢性肺部疾病患者有益。

结论

有大量新证据表明肺康复对COPD和其他慢性肺部疾病患者有益。几个研究领域为未来的研究提供了机会,这些研究可以推动该领域的发展,并使更多符合条件的有需要的患者能够接受康复治疗。

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