Elaini A Bassem, Shetty Sanjay K, Chapman Vernon M, Sahani Dushyant V, Boland Giles W, Sweeney Ann T, Maher Michael M, Slattery James T, Mueller Peter R, Blake Michael A
Department of Radiology, Massachusetts General Hospital, FND 216, 55 Fruit St, Boston, MA 02114, USA.
Radiographics. 2007 May-Jun;27(3):755-67. doi: 10.1148/rg.273055031.
Positron emission tomography (PET)-computed tomography (CT) combines complementary modalities, thereby providing useful structural and functional information for the detection and characterization of a variety of conditions affecting the adrenal gland. The coregistered information provided by PET-CT is often superior to that provided by CT or PET owing to a variety of pitfalls inherent in the use of either modality alone. In addition, PET-CT can prove invaluable in the differentiation between benign and malignant adrenal disease. However, this combined modality also has certain limitations. Benign entities such as lipid-poor adenomas may demonstrate increased uptake at 2-[fluorine 18]fluoro-2-deoxy-d-glucose PET while being indeterminate at standard CT. Moreover, the combined information from PET-CT will not always obviate additional studies or biopsy. Nevertheless, radiologists and nuclear physicians should be familiar with the common as well as the atypical manifestations of adrenal disease at PET and CT. They should also be meticulous in the performance and interpretation of PET-CT, which is crucial for optimal diagnosis and treatment.
正电子发射断层扫描（PET）-计算机断层扫描（CT）结合了互补的检查方式，从而为检测和鉴别影响肾上腺的各种病症提供有用的结构和功能信息。PET-CT提供的配准信息通常优于单独使用CT或PET所提供的信息，这是因为单独使用这两种检查方式中的任何一种都存在各种缺陷。此外，PET-CT在鉴别肾上腺良性和恶性疾病方面可能具有极高价值。然而，这种联合检查方式也存在一定局限性。诸如低脂质腺瘤等良性病变在2-[氟-18]氟-2-脱氧-D-葡萄糖PET检查时可能显示摄取增加，而在标准CT检查中表现不明确。此外，PET-CT的综合信息并不总是能避免进行额外检查或活检。尽管如此，放射科医生和核医学医生应熟悉PET和CT检查时肾上腺疾病的常见及非典型表现。他们还应在PET-CT检查的操作和解读过程中一丝不苟，这对于实现最佳诊断和治疗至关重要。
