Ryan Terence J
Oxford International Wound Healing Foundation, Oxford, UK.
Curr Opin Infect Dis. 2007 Apr;20(2):124-8. doi: 10.1097/QCO.0b013e32801a3e7c.
Wound infection has always been an unconquered problem temporarily improved with the discovery of antibiotics but now struggling with an epidemic of resistant organisms. Wound healing has become a popular sub-speciality for the doctor and allied health professional working in the laboratory or at the bedside. It is a field with many new journals and frequent congresses that publish elaborate proceedings. These have been examined for this review.
Measurement of infection remains elusive. A clear difference between contamination and infection is difficult to delineate. In the era of the HIV/AIDS epidemic attention is drawn to host factors, which when attended to are as effective in suppressing infection as antisepsis. The bacterial capacity to put on a protective coat known as biofilm is a newly investigated system.
Antisepsis and antibiotics continue to provide a wealth of studies and some new technology. The evidence base, as examined by Cochrane systematic reviews, suggests that our strategy for preventing and dealing with infection of wounds needs further refinement.
伤口感染一直是一个尚未攻克的难题，抗生素的发现曾使其暂时得到改善，但如今却面临着耐药菌流行的困境。伤口愈合已成为在实验室或床边工作的医生及相关医疗专业人员热门的亚专业领域。这是一个有许多新期刊且经常召开大会并发表详尽会议记录的领域。本次综述对这些内容进行了研究。
感染的检测仍然难以捉摸。污染与感染之间的明显区别很难界定。在艾滋病毒/艾滋病流行的时代，人们将注意力转向宿主因素，关注这些因素在抑制感染方面与防腐一样有效。细菌形成称为生物膜的保护涂层的能力是一个新的研究系统。
防腐和抗生素继续提供大量研究及一些新技术。经Cochrane系统评价审查的证据基础表明，我们预防和处理伤口感染的策略需要进一步完善。
