Braun T, Sepsenwol S
Mol Cell Endocrinol. 1976 Feb;4(3):183-94. doi: 10.1016/0303-7207(76)90037-x.
LH- and FSH-sensitive adenylate cyclase activity was present in homogenates of whole testis tissue as well as in microdissected seminiferous tubules derived from young rats. In homogenates of seminiferous tubules a single adenylate cyclase appears to interact with both LH and FSH through separate hormone-specific receptors. Disruption of testis tissue by homogenization exposes functional FSH and LH receptors which are inaccessible to the hormones in intact cell preparations. These results indicate that in certain seminiferous tubule cell types only a fraction of the total functional receptors present is accessible to the cell surface for interaction with hormone.
促黄体生成素（LH）和促卵泡生成素（FSH）敏感的腺苷酸环化酶活性存在于幼鼠整个睾丸组织的匀浆以及显微解剖的生精小管中。在生精小管匀浆中，单一的腺苷酸环化酶似乎通过不同的激素特异性受体与LH和FSH都发生相互作用。通过匀浆破坏睾丸组织会暴露在完整细胞制剂中激素无法接触到的功能性FSH和LH受体。这些结果表明，在某些生精小管细胞类型中，仅存在的总功能性受体的一部分可到达细胞表面与激素相互作用。
