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非洲人食管癌:从肿瘤标本中建立持续生长的细胞系。

Carcinoma of the esophagus in Africans: establishment of a continuously growing cell line from a tumor specimen.

作者信息

Bey E, Alexander J, Whitcutt J M, Hunt J A, Gear J H

出版信息

In Vitro. 1976 Feb;12(2):107-14. doi: 10.1007/BF02796356.

DOI:10.1007/BF02796356
PMID:174997
Abstract

Biopsy material, from a patient with an esophageal carcinoma of a type occurring relatively frequently in Africans in some regions of Southern Africa, has been adapted to cell culture conditions and has developed into a continuously growing tumor cell line. The cells have a squamous pattern of growth which they maintain, without piling up, even in heavily confluent cultures.

摘要

取自一名食管癌患者的活检材料,该类型食管癌在非洲南部某些地区的非洲人中相对常见,已适应细胞培养条件并发展成为一个持续生长的肿瘤细胞系。这些细胞具有鳞状生长模式,即使在高度汇合的培养物中也能保持这种模式,不会堆积。

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本文引用的文献

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CANCER IN AFRICA, ESPECIALLY IN REGIONS SOUTH OF THE SAHARA.非洲的癌症,尤其是撒哈拉以南地区的癌症。
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Adhesion and Invasion of Breast and Oesophageal Cancer Cells Are Impeded by Anti-LRP/LR-Specific Antibody IgG1-iS18.抗LRP/LR特异性抗体IgG1-iS18可抑制乳腺癌细胞和食管癌细胞的黏附与侵袭。
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Genomic imbalances in esophageal carcinoma cell lines involve Wnt pathway genes.食管癌细胞系中的基因组不平衡涉及 Wnt 通路基因。
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10
Redistribution of β-catenin in response to EGF and lithium signalling in human oesophageal squamous carcinoma cell lines.β-连环蛋白在人食管鳞状癌细胞系中对表皮生长因子(EGF)和锂信号的反应中的重新分布。
Cancer Cell Int. 2003 Aug 15;3:13. doi: 10.1186/1475-2867-3-13. eCollection 2003.
4
Chromosome preparations of leukocytes cultured from human peripheral blood.从人外周血培养的白细胞的染色体标本制备。
Exp Cell Res. 1960 Sep;20:613-6. doi: 10.1016/0014-4827(60)90138-5.
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Oesophageal cancer in the Bantu.
S Afr Med J. 1957 Apr 27;31(17):401-9.
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An approach to the management of carcinoma of the oesophagus in the Bantu.班图人食管癌的一种管理方法。
S Afr Med J. 1969 May 24;43(21):674-9.
7
A permanent heteroploid human cell line with type B glucose-6-phosphate dehydrogenase.具有B型葡萄糖-6-磷酸脱氢酶的永久性异倍体人类细胞系。
Proc Soc Exp Biol Med. 1971 Apr;136(4):1187-91. doi: 10.3181/00379727-136-35455.
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Distribution maps of esophageal cancer among Bantu in the Transkei.
J Natl Cancer Inst. 1969 Oct;43(4):877-89.
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The cancer pattern in Africans of the Transvaal lowveld.德兰士瓦低地非洲人的癌症模式。
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