Gigante Guido, Mattia Maurizio, Del Giudice Paolo
Department of Technologies and Health, Istituto Superiore di Sanità, Viale Regina Elena 299, 00161 Roma, Italy.
Phys Rev Lett. 2007 Apr 6;98(14):148101. doi: 10.1103/PhysRevLett.98.148101. Epub 2007 Apr 4.
We study the dynamics of a noisy network of spiking neurons with spike-frequency adaptation (SFA), using a mean-field approach, in terms of a two-dimensional Fokker-Planck equation for the membrane potential of the neurons and the calcium concentration gating SFA. The long time scales of SFA allow us to use an adiabatic approximation and to describe the network as an effective nonlinear two-dimensional system. The phase diagram is computed for varying levels of SFA and synaptic coupling. Two different population-bursting regimes emerge, depending on the level of SFA in networks with noisy emission rate, due to the finite number of neurons.
我们使用平均场方法,依据神经元膜电位和控制突触频率适应(SFA)的钙浓度的二维福克 - 普朗克方程,研究了具有突触频率适应的脉冲神经元噪声网络的动力学。SFA的长时间尺度使我们能够使用绝热近似,并将该网络描述为一个有效的非线性二维系统。针对不同水平的SFA和突触耦合计算了相图。由于神经元数量有限,在具有噪声发射率的网络中,根据SFA的水平会出现两种不同的群体爆发状态。